[PDF][PDF] Modelling and simulation of the drug release from a solid dosage form in the human ascending colon

M Schütt, K Stamatopoulos, HK Batchelor… - 2021 - research.birmingham.ac.uk
For colonic drug delivery, the ascending part of the colon is the most favourable site as it
offers the most suitable environmental conditions for drug dissolution. Commonly, the …

A Novel Mathematical Framework for the Venous Valve Leaflet Morphology Extracted From In-Vitro Images Using Machine Learning Assisted Stereological Analysis

VMK Kotteda, HF Janssen… - Fluids …, 2021 - asmedigitalcollection.asme.org
It has been suggested that stasis (stagnant zones over a period of time, dependent on other
factors such as age, or underlying medical conditions, such as cancer or covid19) in the …

Two case studies of SPH modelling in biological system: large intestine and deep vein valves

W Wen - 2018 - etheses.bham.ac.uk
Computational Fluid Dynamics (CFD) techniques has proven its adaptiveness and mutuality
in various application for diversified fields. At the moment, the investigation of physical …

[PDF][PDF] Patient-specific design of the right ventricle to pulmonary artery conduit via computational analysis

P Ebrahimi - 2019 - core.ac.uk
Cardiovascular prostheses are routinely used in surgical procedures to address congenital
malformations, for example establishing a pathway from the right ventricle to the pulmonary …

Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model

M Schütt, C O'Farrell… - …, 2019 - nottingham-repository.worktribe.com
The performance of solid oral dosage forms targeting the colon is typically evaluated using
standardised pharmacopeial dissolution apparatuses. However, these fail to replicate …

Nanoparticle-membrane interactions

Q Yu - 2017 - kups.ub.uni-koeln.de
Biological membranes are fluid thin films composed of lipids, proteins and sugars.
Nanoparticles are one specific nano-scale cargo that can be engineered with controlled …

A Discrete Approach to Meshless Lagrangian Solid Modeling

M Marko - Computation, 2017 - mdpi.com
The author demonstrates a stable Lagrangian solid modeling method, tracking the
interactions of solid mass particles rather than using a meshed grid. This numerical method …