Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Non-viral vectors in gene therapy: recent development, challenges, and prospects

H Zu, D Gao - The AAPS journal, 2021 - Springer
Gene therapy has been experiencing a breakthrough in recent years, targeting various
specific cell groups in numerous therapeutic areas. However, most recent clinical studies …

Liquid exfoliation of ultrasmall zirconium carbide nanodots as a noninflammatory photothermal agent in the treatment of glioma

D Liu, X Dai, W Zhang, X Zhu, Z Zha, H Qian, L Cheng… - Biomaterials, 2023 - Elsevier
Photothermal therapy (PTT), like other clinical translational tumor ablation techniques,
requires a temperature increase above 50° C to cause necrosis and death of tumor cells …

Chitosan based materials in cosmetic applications: A review

K Kulka, A Sionkowska - Molecules, 2023 - mdpi.com
This review provides a report on the properties and recent advances in the application of
chitosan and chitosan-based materials in cosmetics. Chitosan is a polysaccharide that can …

Cationic polymers as transfection reagents for nucleic acid delivery

X Cai, R Dou, C Guo, J Tang, X Li, J Chen, J Zhang - Pharmaceutics, 2023 - mdpi.com
Nucleic acid therapy can achieve lasting and even curative effects through gene
augmentation, gene suppression, and genome editing. However, it is difficult for naked …

Chitosan-based scaffold for mineralized tissues regeneration

T Sukpaita, S Chirachanchai, A Pimkhaokham… - Marine Drugs, 2021 - mdpi.com
Conventional bone grafting procedures used to treat bone defects have several limitations.
An important aspect of bone tissue engineering is developing novel bone substitute …

CircPAK1 promotes the progression of hepatocellular carcinoma via modulation of YAP nucleus localization by interacting with 14-3-3ζ

X Hao, Y Zhang, X Shi, H Liu, Z Zheng, G Han… - Journal of Experimental …, 2022 - Springer
Abstract Background Circular RNA (circRNA), a new class of non-coding RNA, has obvious
correlations with the occurrence and development of many diseases, including tumors. This …

Chitosan nanoparticles and based composites as a biocompatible vehicle for drug delivery: a review

R Pathak, S Bhatt, VD Punetha, M Punetha - International Journal of …, 2023 - Elsevier
The shellfish processing industry is one of the largest growing industries across the globe
with a market size of around USD 62B. However, it also leads to a significant environmental …

Chitosan-based nanosystems for cancer diagnosis and therapy: Stimuli-responsive, immune response, and clinical studies

FD Moghaddam, EN Zare, M Hassanpour… - Carbohydrate …, 2024 - Elsevier
Cancer, a global health challenge of utmost severity, necessitates innovative approaches
beyond conventional treatments (eg, surgery, chemotherapy, and radiation therapy) …

Chitosan-based nanoparticles for nucleic acid delivery: technological aspects, applications, and future perspectives

M Karayianni, T Sentoukas, A Skandalis, N Pippa… - Pharmaceutics, 2023 - mdpi.com
Chitosan is a naturally occurring polymer derived from the deacetylation of chitin, which is
an abundant carbohydrate found mainly in the shells of various marine and terrestrial …