Insights on the use of α-lipoic acid for therapeutic purposes

B Salehi, Y Berkay Yılmaz, G Antika… - Biomolecules, 2019 - mdpi.com
α-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants,
animals, and humans. It has various properties, among them great antioxidant potential and …

The effect of vitamin E supplementation on selected inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials

O Asbaghi, M Sadeghian, B Nazarian… - Scientific reports, 2020 - nature.com
The previous meta-analysis of clinical trials revealed a beneficial effect of vitamin E
supplementation on serum C-reactive protein (CRP) concentrations; however, it is unknown …

Safety evaluation of α-lipoic acid supplementation: A systematic review and meta-analysis of randomized placebo-controlled clinical studies

F Fogacci, M Rizzo, C Krogager, C Kennedy… - Antioxidants, 2020 - mdpi.com
Alpha-lipoic acid (ALA) is a natural short-chain fatty acid that has attracted great attention in
recent years as an antioxidant molecule. However, some concerns have been recently …

Lipoic acid. Kinetics and pluripotent biological properties and derivatives

P Theodosis-Nobelos, G Papagiouvannis… - Molecular Biology …, 2021 - Springer
Lipoic acid (LA) is globally known and its supplements are widely used. Despite its
importance for the organism it is not considered a vitamin any more. The multiple metabolic …

Current innovations in nutraceuticals and functional foods for intervention of non-alcoholic fatty liver disease

M Zhao, S Chen, X Ji, X Shen, J You, X Liang… - Pharmacological …, 2021 - Elsevier
As innovations in global agricultural production and food trading systems lead to major
dietary shifts, high morbidity rates from non-alcoholic fatty liver disease (NAFLD) …

Alpha‐lipoic acid: A possible pharmacological agent for treating dry eye disease and retinopathy in diabetes

TA Ajith - Clinical and Experimental Pharmacology and …, 2020 - Wiley Online Library
Alpha‐lipoic acid (ALA) is a naturally occurring dithiol micronutrient which acts as a cofactor
for mitochondrial enzyme activity. Due to its potential antioxidant activity, it is considered as …

[HTML][HTML] Bioactive compounds in childhood obesity and associated metabolic complications: Current evidence, controversies and perspectives

G Fiore, MC Pascuzzi, E Di Profio, A Corsello… - Pharmacological …, 2023 - Elsevier
Obesity represents the most frequent chronic disease among children worldwide, with a
significant global burden on society. Metabolically unhealthy obesity (MUO) can affect …

Alpha‐lipoic acid supplementation significantly reduces the risk of obesity in an updated systematic review and dose response meta‐analysis of randomised placebo …

M Vajdi, M Abbasalizad Farhangi - International Journal of …, 2020 - Wiley Online Library
Background There are numerous trials reported the effect of alpha‐lipoic acid (ALA) on
obesity measurements; while no summarised dose‐response meta‐analysis is available to …

The effect of hydroxy citric acid supplementation with calorie-restricted diet on metabolic, atherogenic and inflammatory biomarkers in women with non-alcoholic fatty …

S Arefhosseini, H Tutunchi, S Nomi-Golzar… - Food & Function, 2022 - pubs.rsc.org
The objective of the present study was to examine the effects of hydroxy citric acid (HCA)
extracts from Garcinia cambogia on metabolic, atherogenic and inflammatory biomarkers in …

A metagenomic study identifies a Prevotella copri enriched microbial profile associated with non‐alcoholic steatohepatitis in subjects with obesity

S Moran‐Ramos, D Cerqueda‐García… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is the most
common cause of liver disease. Increasing evidence indicates that the gut microbiota can …