[HTML][HTML] Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
Microbe–host communication is essential to maintain vital functions of a healthy host, and its
disruption has been associated with several diseases, including Crohn's disease and …

[HTML][HTML] Akkermansia muciniphila as a Next-Generation Probiotic in Modulating Human Metabolic Homeostasis and Disease Progression: A Role Mediated by Gut …

H Jian, Y Liu, X Wang, X Dong, X Zou - International Journal of Molecular …, 2023 - mdpi.com
Appreciation of the importance of Akkermansia muciniphila is growing, and it is becoming
increasingly relevant to identify preventive and/or therapeutic solutions targeting gut–liver …

Gut dysbiosis promotes preeclampsia by regulating macrophages and trophoblasts

J Jin, L Gao, X Zou, Y Zhang, Z Zheng… - Circulation …, 2022 - Am Heart Assoc
Background: Preeclampsia is one of the leading causes of maternal and perinatal morbidity
and is characterized by hypertension, inflammation, and placental dysfunction. Gut …

A next-generation probiotic: Akkermansia muciniphila ameliorates chronic stress–induced depressive-like behavior in mice by regulating gut microbiota and …

Y Ding, F Bu, T Chen, G Shi, X Yuan, Z Feng… - Applied Microbiology …, 2021 - Springer
Major depressive disorder (MDD) is a neurasthenic disease, which is the second-largest
burden of disease globally. Increasing studies have revealed that depression is associated …

[HTML][HTML] Stronger gut microbiome modulatory effects by postbiotics than probiotics in a mouse colitis model

T Zhang, W Zhang, C Feng, LY Kwok, Q He… - npj Science of Food, 2022 - nature.com
Probiotics are increasingly used as adjunctive therapy to manage gastrointestinal diseases,
such as ulcerative colitis. However, probiotic use has posed some safety concerns. Thus …

A polysaccharide from Rosa roxburghii Tratt fruit attenuates high-fat diet-induced intestinal barrier dysfunction and inflammation in mice by modulating the gut …

L Wang, P Zhang, C Li, F Xu, J Chen - Food & function, 2022 - pubs.rsc.org
Obesity-induced colonic inflammation-stimulated colitis is one of the main causes of
colorectal cancer. Dietary polysaccharides are considered an effective agent for relieving …

Bifidobacterium and Lactobacillus improve inflammatory bowel disease in zebrafish of different ages by regulating the intestinal mucosal barrier and microbiota

Y Ni, Y Zhang, L Zheng, N Rong, Y Yang, P Gong… - Life Sciences, 2023 - Elsevier
Aims Inflammatory bowel disease (IBD) patients are accompanied by impaired intestinal
barrier integrity and gut microbiota dysbiosis. Strategies targeting the gut microbiota are …

[HTML][HTML] Mulberry anthocyanins ameliorate DSS-induced ulcerative colitis by improving intestinal barrier function and modulating gut microbiota

J Mo, J Ni, M Zhang, Y Xu, Y Li, N Karim, W Chen - Antioxidants, 2022 - mdpi.com
Mulberry has attracted wide attention due to its substantial nutritional values. This work first
studied the protective effect of mulberry anthocyanins (MAS) on dextran sulfate sodium …

[HTML][HTML] The negative effect of Akkermansia muciniphila-mediated post-antibiotic reconstitution of the gut microbiota on the development of colitis-associated …

K Wang, W Wu, Q Wang, L Yang, X Bian… - Frontiers in …, 2022 - frontiersin.org
The bidirectional relationship between colorectal cancer (CRC) and the gut microbiome has
been well-documented. Here, we investigated the impact of Akkermansia muciniphila …

[HTML][HTML] Excessive consumption of mucin by over-colonized Akkermansia muciniphila promotes intestinal barrier damage during malignant intestinal environment

S Qu, Y Zheng, Y Huang, Y Feng, K Xu… - Frontiers in …, 2023 - frontiersin.org
Gut microbiota disorders damage the intestinal barrier, which causes intestinal disease.
Thus, we screened the microbiota with significant changes using an in situ malignant …