Involvement of the long noncoding RNA H19 in osteogenic differentiation and bone regeneration

Z Zhou, MS Hossain, D Liu - Stem Cell Research & Therapy, 2021 - Springer
Osteogenic differentiation and bone regeneration are complex processes involving multiple
genes and multiple steps. In this review, we summarize the effects of the long noncoding …

Regulatory mechanisms for the development of growth plate cartilage

T Michigami - Cellular and Molecular Life Sciences, 2013 - Springer
In vertebrates, most of the skeleton is formed through endochondral ossification.
Endochondral bone formation is a complex process involving the mesenchymal …

[HTML][HTML] Oxidized alginate hydrogels with the GHK peptide enhance cord blood mesenchymal stem cell osteogenesis: A paradigm for metabolomics-based evaluation …

ME Klontzas, S Reakasame, R Silva, JCF Morais… - Acta biomaterialia, 2019 - Elsevier
Oxidized alginate hydrogels are appealing alternatives to natural alginate due to their
favourable biodegradability profiles and capacity to self-crosslink with amine containing …

Epigenetic regulation of bone mass

EM Curtis, NR Fuggle, C Cooper, NC Harvey - Best Practice & Research …, 2022 - Elsevier
Osteoporosis, characterised by low bone mass, poor bone structure, and an increased risk
of fracture, is a major public health problem. There is increasing evidence that the influence …

Epigenetic mechanisms of bone regeneration and homeostasis

Y Liu, XL Zhang, L Chen, X Lin, D Xiong, F Xu… - Progress in Biophysics …, 2016 - Elsevier
Bone regeneration is a promising avenue for osteoporosis (OP) treatment. It consists of
several procedures, such as the osteogenic differentiation of mesenchymal stem cells as …

Changes in DNA methylation accompany changes in gene expression during chondrocyte hypertrophic differentiation in vitro

P Singh, SG Lessard, P Mukherjee… - Annals of the New …, 2021 - Wiley Online Library
During osteoarthritis (OA), articular chondrocytes undergo phenotypic changes that
resemble developmental patterns characteristic of growth plate chondrocytes. These …

Intraspecific and interspecific investigations of skeletal DNA methylation and femur morphology in primates

G Housman, EE Quillen… - American journal of …, 2020 - Wiley Online Library
Objectives Epigenetic mechanisms influence the development and maintenance of complex
phenotypes and may also contribute to the evolution of species–specific phenotypes. With …

Endocrine-disrupting chemicals, epigenetics, and skeletal system dysfunction: exploration of links using bisphenol A as a model system

F Xin, LM Smith, M Susiarjo… - Environmental …, 2018 - academic.oup.com
Early life exposures to endocrine-disrupting chemicals (EDCs) have been associated with
physiological changes of endocrine-sensitive tissues throughout postnatal life. Although …

DNA methylation profile discriminates sporadic giant cell granulomas of the jaws and cherubism from their giant cell‐rich histological mimics

LM Guimarães, D Baumhoer, V Andrei… - The Journal of …, 2023 - Wiley Online Library
Sporadic giant cell granulomas (GCGs) of the jaws and cherubism‐associated giant cell
lesions share histopathological features and microscopic diagnosis alone can be …

Epigenetic pathways regulating bone homeostasis: potential targeting for intervention of skeletal disorders

JAR Gordon, MA Montecino, RI Aqeilan… - Current osteoporosis …, 2014 - Springer
Epigenetic regulation utilizes different mechanisms to convey heritable traits to progeny cells
that are independent of DNA sequence, including DNA silencing, post-translational …