Emerging biomarkers for the detection of cardiovascular diseases

S Thupakula, SSR Nimmala, H Ravula… - The Egyptian Heart …, 2022 - Springer
Background The prevalence of cardiovascular disease (CVD) has been continuously
increasing, and this trend is projected to continue. CVD is rapidly becoming a significant …

Mass spectrometry-based proteomic technology and its application to study skeletal muscle cell biology

P Dowling, D Swandulla, K Ohlendieck - Cells, 2023 - mdpi.com
Voluntary striated muscles are characterized by a highly complex and dynamic proteome
that efficiently adapts to changed physiological demands or alters considerably during …

Quantitative proteomic analysis of skeletal muscles from wild-type and transgenic mice carrying recessive Ryr1 mutations linked to congenital myopathies

J Eckhardt, A Ruiz, S Koenig, M Frieden, H Meier… - Elife, 2023 - elifesciences.org
Skeletal muscles are a highly structured tissue responsible for movement and metabolic
regulation, which can be broadly subdivided into fast and slow twitch muscles with each type …

Nitrosative Stress in Astronaut Skeletal Muscle in Spaceflight

D Blottner, M Moriggi, G Trautmann, S Furlan, K Block… - Antioxidants, 2024 - mdpi.com
Long-duration mission (LDM) astronauts from the International Space Station (ISS)(> 180
ISS days) revealed a close-to-normal sarcolemmal nitric oxide synthase type-1 (NOS1) …

Comparative proteomic analysis of glycolytic and oxidative muscle in pigs

X Tan, Y He, Y He, Z Yan, J Chen, R Zhao, X Sui… - Genes, 2023 - mdpi.com
The quality of meat is highly correlated with muscle fiber type. However, the mechanisms via
which proteins regulate muscle fiber types in pigs are not entirely understood. In the current …

Proteomic profiling of impaired excitation–contraction coupling and abnormal calcium handling in muscular dystrophy

P Dowling, S Gargan, D Swandulla, K Ohlendieck - Proteomics, 2022 - Wiley Online Library
The X‐linked inherited neuromuscular disorder Duchenne muscular dystrophy is
characterised by primary abnormalities in the membrane cytoskeletal component dystrophin …

First comparison of early post-mortem proteomes in two goat muscle types: M. Longissimus thoracis and M. semitendinosus

A della Malva, M Lamri, M Albenzio, M Gagaoua - Food Bioscience, 2023 - Elsevier
This study aimed to characterize and compare the muscle proteomes of goat Longissimus
thoracis (LT) and Semitendinosus (ST) muscles taken early post-mortem from young …

How Can Proteomics Help to Elucidate the Pathophysiological Crosstalk in Muscular Dystrophy and Associated Multi-System Dysfunction?

P Dowling, C Trollet, E Negroni, D Swandulla… - Proteomes, 2024 - mdpi.com
This perspective article is concerned with the question of how proteomics, which is a core
technique of systems biology that is deeply embedded in the multi-omics field of modern …

A Combined Differential Proteome and Transcriptome Profiling of Fast-and Slow-Twitch Skeletal Muscle in Pigs

W Wei, C Zha, A Jiang, Z Chao, L Hou, H Liu, R Huang… - Foods, 2022 - mdpi.com
Skeletal muscle fiber types can contribute in part to affecting pork quality parameters. Biceps
femoris (Bf)(fast muscle or white muscle) and Soleus (Sol)(slow muscle or red muscle) are …

The ameliorative role of germinated fenugreek and barley grains on the structure and function of offspring's tibialis muscle maternally fed on high fat diet

FA Hassan Megahed, HIH El-Sayyad… - Egyptian Journal of …, 2024 - Taylor & Francis
This research demonstrates the impact of maternal high fat diet (HFD) consumption on the
structure and function of the rat offspring tibialis muscle and investigates the protective …