Polypill for cardiovascular disease prevention: systematic review and meta-analysis of randomized controlled trials

MMG Mohamed, M Osman, B Kheiri, M Saleem… - International Journal of …, 2022 - Elsevier
Background Cardiovascular disease is the leading cause of death worldwide. Although
many pharmacological agents exist, drug compliance and therapeutic goal achievement …

Statin's role on blood pressure levels: Meta‐analysis based on randomized controlled trials

HT Liu, NH Deng, ZF Wu, ZY Zhou… - The Journal of …, 2023 - Wiley Online Library
Statins have been proven to be effective in minimizing the risk of cardiovascular adverse
events, however, their effect on BP variability is debatable with respect to their significance …

Antihypertensive effects of rosuvastatin in patients with hypertension and dyslipidemia: A systemic review and meta-analysis of randomized studies

S Lee, S Yang, MJ Chang - PloS one, 2021 - journals.plos.org
Some studies have suggested the antihypertensive effects of statins, a class of lipid-lowering
agents, particularly in patients with hypertension. However, the evidence for the role of …

Effectiveness of the Combination of Enalapril and Nifedipine for the Treatment of Hypertension versus Empirical Treatment in Primary Care Patients

H Badillo-Alonso, M Martínez-Alanis… - Journal of …, 2023 - mdpi.com
Hypertension in Mexico has a prevalence of 32% and is the second most widespread cause
of consultation in primary care. Only 40% of patients in treatment have a blood pressure (BP) …

Efficacy and safety of co‐administered telmisartan/amlodipine and rosuvastatin in subjects with hypertension and dyslipidemia

X Jin, MH Kim, KH Han, SJ Hong… - The Journal of …, 2020 - Wiley Online Library
Single risk factors, such as hypertension and dyslipidemia, can combine to exacerbate the
development and severity of cardiovascular disease. Treatment goals may be more …

A randomized, double‐blind clinical trial to evaluate the efficacy and safety of a fixed‐dose combination of amlodipine/rosuvastatin in patients with dyslipidemia and …

W Kim, K Chang, EJ Cho, JC Ahn… - The Journal of …, 2020 - Wiley Online Library
This multicenter, randomized, double‐blind, parallel‐group phase III clinical trial aimed to
investigate the efficacy and safety of a rosuvastatin+ amlodipine combination compared with …

Clinical effectiveness and safety of amlodipine/losartan‐based single‐pill combination therapy in patients with hypertension: Findings from real‐world, multicenter …

J Lee, J Choi, Y Yum, HJ Joo, YH Kim… - The Journal of …, 2021 - Wiley Online Library
Various single‐pill combinations (SPCs) have been introduced to improve drug compliance
and clinical efficacy. However, there is a lack of real‐world evidence regarding the …

Fixed‐dose combination of amlodipine and atorvastatin improves clinical outcomes in patients with concomitant hypertension and dyslipidemia

CP Lin, YC Tung, FC Hsiao, CH Yang… - The Journal of …, 2020 - Wiley Online Library
Hypertension and dyslipidemia are important risk factors for cardiovascular disease.
However, the clinical outcomes of fixed‐dose combination (FDC) versus free‐equivalent …

Efficacy and safety of combination therapy with telmisartan, rosuvastatin, and ezetimibe in patients with dyslipidemia and hypertension: A randomized, double‐blind …

CJ Lee, WC Kang, SH Ihm, IS Sohn… - The Journal of …, 2024 - Wiley Online Library
This study aimed to compare and evaluate the efficacy of the blood pressure (BP) control
and cholesterol‐lowering effects and safety of combination therapy with telmisartan …

[HTML][HTML] Beneficial effects of fixed-dose combination of amlodipine and atorvastatin in patients with concomitant hypertension and hypercholesterolemia: a multi …

CP Lin, FC Hsiao, CT Wu, YS Lin, SW Chen… - Acta Cardiologica …, 2022 - ncbi.nlm.nih.gov
Background Blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) are
important risk factors for cardiovascular (CV) diseases. Although treating these factors …