ATP-binding cassette (ABC) transporters are involved in active pumping of many diverse
substrates through the cellular membrane. The transport mediated by these proteins …

The steroid hormones progestagens, estrogens, androgens, and glucocorticoids as well as
their precursor cholesterol are required for successful establishment and maintenance of …

The placenta is a key organ in fetal growth and development because it controls maternal-to-
fetal exchanges of nutrients and hormones. It also interferes with drug delivery to the fetus by …

Data obtained from recent studies in humans, rodents, and cell culture demonstrate that
circulating maternal cholesterol can be transported to the fetus. The two major cell types …

Cholesterol is required for fetal development. Data obtained from recent studies in humans,
rodents, and cell cultures showed that circulating maternal cholesterol can affect fetal …

The human placenta fulfills a variety of essential functions during prenatal life. Several ABC
transporters are expressed in the human placenta, where they play a role in the transport of …

Lipoprotein lipid physiology in pregnancy has important implications for the developing fetus
and newborn as well as the mother. Cholesterol and essential fatty acids are essential for …

In vitro models have proven to be effective in studying the placental transporters that play a
role in the exchange of nutrients, waste products, and drugs between the maternal and fetal …

Background Macrosomia is a serious public health problem worldwide due to its increasing
prevalence and adverse influences on maternal and neonatal outcomes. Maternal …

The unique properties of nanoparticles (NP) are key to the excitement over their potential
application to benefit many aspects of our lives, but are also the cause of concern over …