Helminth infections and host immune regulation
HJ McSorley, RM Maizels - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …
regions. However, regions where helminth parasites are endemic record much lower …
[HTML][HTML] Making mouse models that reflect human immune responses
L Tao, TA Reese - Trends in immunology, 2017 - cell.com
Humans are infected with a variety of acute and chronic pathogens over the course of their
lives, and pathogen-driven selection has shaped the immune system of humans. The same …
lives, and pathogen-driven selection has shaped the immune system of humans. The same …
Emphasizing the ecology in parasite community ecology
AB Pedersen, A Fenton - Trends in ecology & evolution, 2007 - cell.com
In natural systems, individuals are often co-infected by many species of parasites. However,
the significance of interactions between species and the processes that shape within-host …
the significance of interactions between species and the processes that shape within-host …
Immunity against helminths: interactions with the host and the intercurrent infections
E Moreau, A Chauvin - BioMed Research International, 2010 - Wiley Online Library
Helminth parasites are of considerable medical and economic importance. Studies of the
immune response against helminths are of great interest in understanding interactions …
immune response against helminths are of great interest in understanding interactions …
[HTML][HTML] Controlling soil-transmitted helminthiasis in pre-school-age children through preventive chemotherapy
M Albonico, H Allen, L Chitsulo, D Engels… - PLoS neglected …, 2008 - journals.plos.org
Pre-school age children account for 10%–20% of the 2 billion people worldwide who are
infected with soil-transmitted helminths (STHs): Ascaris lumbricoides (roundworm), Trichuris …
infected with soil-transmitted helminths (STHs): Ascaris lumbricoides (roundworm), Trichuris …
Impairment of dendritic cell function by excretory‐secretory products: a potential mechanism for nematode‐induced immunosuppression
M Segura, Z Su, C Piccirillo… - European journal of …, 2007 - Wiley Online Library
To determine whether helminth‐derived products modulate dendritic cell (DC) function, we
investigated the effects of excretory‐secretory products (ES) and adult worm homogenate …
investigated the effects of excretory‐secretory products (ES) and adult worm homogenate …
[HTML][HTML] Helminthiases; prevalence, transmission, host-parasite interactions, resistance to common synthetic drugs and treatment
OA Idris, OA Wintola, AJ Afolayan - Heliyon, 2019 - cell.com
The morbidity caused by parasite worms on susceptible hosts is of great concern and
studies were carried out to explain the mechanism of infection, prevalence, host-parasite …
studies were carried out to explain the mechanism of infection, prevalence, host-parasite …
[HTML][HTML] Helminth infections suppress the efficacy of vaccination against seasonal influenza
W Hartmann, ML Brunn, N Stetter, N Gagliani… - Cell reports, 2019 - cell.com
Helminth parasites infect more than a quarter of the human population and inflict significant
changes to the immunological status of their hosts. Here, we analyze the impact of helminth …
changes to the immunological status of their hosts. Here, we analyze the impact of helminth …
[HTML][HTML] Do parasite infections interfere with immunisation? A review and meta-analysis
Immune responses to vaccination are heterogeneous between individuals; the same
vaccine that provides protection in one circumstance may be ineffective in another. One …
vaccine that provides protection in one circumstance may be ineffective in another. One …
Immune modulation and modulators in Heligmosomoides polygyrus infection
RM Maizels, JP Hewitson, J Murray, YM Harcus… - Experimental …, 2012 - Elsevier
The intestinal nematode parasite Heligmosomoides polygyrus bakeri exerts widespread
immunomodulatory effects on both the innate and adaptive immune system of the host …
immunomodulatory effects on both the innate and adaptive immune system of the host …