The WAG/Rij strain: a genetic animal model of absence epilepsy with comorbidity of depressiony
K Sarkisova, G van Luijtelaar - Progress in Neuro-Psychopharmacology …, 2011 - Elsevier
A great number of clinical observations show a relationship between epilepsy and
depression. Idiopathic generalized epilepsy, including absence epilepsy, has a genetic …
depression. Idiopathic generalized epilepsy, including absence epilepsy, has a genetic …
The genetic absence epilepsy rat from Strasbourg as a model to decipher the neuronal and network mechanisms of generalized idiopathic epilepsies
A Depaulis, O David, S Charpier - Journal of neuroscience methods, 2016 - Elsevier
First characterized in 1982, the genetic absence epilepsy rat from Strasbourg (GAERS) has
emerged as an animal model highly reminiscent of a specific form of idiopathic generalized …
emerged as an animal model highly reminiscent of a specific form of idiopathic generalized …
Disrupted basal ganglia–thalamocortical loops in focal to bilateral tonic-clonic seizures
Focal to bilateral tonic-clonic seizures are associated with lower quality of life, higher risk of
seizure-related injuries, increased chance of sudden unexpected death, and unfavourable …
seizure-related injuries, increased chance of sudden unexpected death, and unfavourable …
The process of epileptogenesis: a pathophysiological approach
NO Dalby, I Mody - Current opinion in neurology, 2001 - journals.lww.com
Several recent advances have contributed to our understanding of the processes associated
with mesial temporal lobe epilepsy in humans and in experimental animal models. Common …
with mesial temporal lobe epilepsy in humans and in experimental animal models. Common …
Upholding WAG/Rij rats as a model of absence epileptogenesis: Hidden mechanisms and a new theory on seizure development
The WAG/Rij rat model has recently gathered attention as a suitable animal model of
absence epileptogenesis. This latter term has a broad definition encompassing any possible …
absence epileptogenesis. This latter term has a broad definition encompassing any possible …
High-frequency stimulation of the sub-thalamic nucleus suppresses absence seizures in the rat: comparison with neurotoxic lesions
High-frequency electrical stimulation of deep brain structures has recently been developed
for the surgical approach of neurologic disorders. Applied to the thalamus in tremors or to …
for the surgical approach of neurologic disorders. Applied to the thalamus in tremors or to …
[图书][B] Textbook of epilepsy surgery
HO Luders - 2008 - books.google.com
Textbook of Epilepsy Surgery covers all of the latest advances in the surgical management
of epilepsy. The book provides a better understanding of epileptogenic mechanisms in …
of epilepsy. The book provides a better understanding of epileptogenic mechanisms in …
Resting state basal ganglia network in idiopathic generalized epilepsy
The basal ganglia, a brain structure related to motor control, is implicated in the modulation
of epileptic discharges generalization in patients with idiopathic generalized epilepsy (IGE) …
of epileptic discharges generalization in patients with idiopathic generalized epilepsy (IGE) …
Where fMRI and electrophysiology agree to disagree: corticothalamic and striatal activity patterns in the WAG/Rij rat
AM Mishra, DJ Ellens, U Schridde… - Journal of …, 2011 - Soc Neuroscience
The relationship between neuronal activity and hemodynamic changes plays a central role
in functional neuroimaging. Under normal conditions and in neurological disorders such as …
in functional neuroimaging. Under normal conditions and in neurological disorders such as …
SLCO5A1 and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsy
D Roshandel, EJ Sanders, A Shakeshaft… - npj Genomic …, 2023 - nature.com
Elevated impulsivity is a key component of attention-deficit hyperactivity disorder (ADHD),
bipolar disorder and juvenile myoclonic epilepsy (JME). We performed a genome-wide …
bipolar disorder and juvenile myoclonic epilepsy (JME). We performed a genome-wide …