The link between chronic immune activation and tumorigenesis is well established.
Compelling evidence has accumulated that histologic assessment of infiltration patterns of …

Intraventricular hemorrhage (IVH) occurs in 20% to 25% of very low birthweight preterm
neonates and may be associated with significant sequelae. Infants who have IVH are at risk …

Lung cancer is the foremost cause of cancer-related deaths world-wide. Both, the major
forms of lung cancer, Non-small cell lung cancer (NSCLC) and Small cell lung cancers …

The Erb-B family of receptors plays an important role in lung carcinogenesis and tumor
development, and EGFR and HER2 are highly expressed in bronchial preneoplasia. In …

Purpose To investigate whether mRNA expression levels of cyclin D1 (CCND1),
cyclooxygenase 2 (Cox-2), epidermal growth factor receptor (EGFR), interleukin 8 (IL-8), and …

For centuries, nonsteroidal anti-inflammatory drugs (NSAIDs) have been part of our clinical
practice. They started out as drugs with anti-inflammatory and analgesic action, and …

Cyclooxygenase (COX)-2, a rate-limiting enzyme of prostaglandin (PG) production, is
overexpressed in colorectal adenomas and adenocarcinomas, and its inhibition by …

Tobacco carcinogens induce Akt activation and lung carcinogenesis. We previously
demonstrated that deguelin, a natural plant product, specifically inhibits the proliferation of …

BACKGROUND: The statistics on lung cancer necessitates the urge to develop new
methods to control this most deadly form of cancer. Chemoprevention is one of these new …

Lung cancer is a well-known malignant tumor of the respiratory tract, which has caused a
significant level of damage to human health in the 21st century. Micro-RNAs (miRNAs) are …