Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

Anaphylaxis is an acute, potential life-threatening systemic allergic reaction that may have a
wide range of clinical manifestations. Severe anaphylaxis and/or the need for repeated …

Background To examine the effectiveness and safety of yoga of women with sleep problems
by performing a systematic review and meta-analysis. Methods Medline/PubMed …

Importance Insomnia disorder is prevalent and associated with health risks in older adults;
however, efficacy and safety issues with existing treatments create significant unmet needs …

Abstract Background Although the Coronavirus Disease 2019 (COVID-19) has greatly
impacted individuals' mental health and quality of life, network analysis studies of …

Chronic insomnia affects 57% of the elderly in the United States, with impairment of quality
of life, function, and health. Chronic insomnia burdens society with billions of dollars in direct …

Background Polypharmacy and inappropriate drug use cause numerous complications,
such as cognitive impairment, frailty, falls, and functional dependence. The present study …

Abstract Study Objectives This randomized, double-blind, placebo-controlled, crossover
study was conducted to evaluate the safety and efficacy of 2 weeks of nightly sublingual …

Sleep complaints can be both common and complex in the older patient. Their consideration
is an important aspect of holistic care, and may have an impact on quality of life, mortality …

Objective To assess the dose-response of daridorexant, a new dual orexin receptor
antagonist, on wake after sleep onset (WASO). Methods Elderly (≥ 65 years) participants …