Iron in multiple sclerosis: roles in neurodegeneration and repair
MRI and histological studies have shown global alterations in iron levels in the brains of
patients with multiple sclerosis (MS), including increases in the iron stored by macrophages …
patients with multiple sclerosis (MS), including increases in the iron stored by macrophages …
Insight into the role of chondroitin sulfate E in angiogenesis
P Kastana, E Choleva, E Poimenidi… - The FEBS …, 2019 - Wiley Online Library
Chondroitin sulfate E (CS‐E) is a glycosaminoglycan containing type‐E disaccharide units
(sulfated at C‐4 and C‐6 of N‐acetylgalactosamine). CS‐E is covalently linked to a core …
(sulfated at C‐4 and C‐6 of N‐acetylgalactosamine). CS‐E is covalently linked to a core …
Engineered sulfated polysaccharides for biomedical applications
Sulfated polysaccharides are ubiquitous in living systems and have central roles in
biological functions such as organism development, cell proliferation and differentiation …
biological functions such as organism development, cell proliferation and differentiation …
Keratan sulfate (KS)‐proteoglycans and neuronal regulation in health and disease: the importance of KS‐glycodynamics and interactive capability with …
J Melrose - Journal of Neurochemistry, 2019 - Wiley Online Library
Compared to the other classes of glycosaminoglycans (GAG s), that is, chondroitin/dermatan
sulfate, heparin/heparan sulfate and hyaluronan, keratan sulfate (KS), have the least known …
sulfate, heparin/heparan sulfate and hyaluronan, keratan sulfate (KS), have the least known …
Chondroitin sulfate E alleviates β-amyloid toxicity in transgenic Caenorhabditis elegans by inhibiting its aggregation
X Wang, Y Yang, J Zou, Y Li, XG Zhang - International Journal of Biological …, 2022 - Elsevier
Abstract Chondroitin sulfate E (CS-E), which is characterized by oversulfated disaccharide
units, has been shown to regulate neuronal adhesion, neurite outgrowth and exert …
units, has been shown to regulate neuronal adhesion, neurite outgrowth and exert …
Enhancing the expression of chondroitin 4-O-sulfotransferase for one-pot enzymatic synthesis of chondroitin sulfate A
W Zhang, P Zhang, H Wang, R Xu, Z Xie, Y Wang… - Carbohydrate …, 2024 - Elsevier
Chondroitin sulfate (CS) stands as a pivotal compound in dietary supplements for
osteoarthritis treatment, propelling significant interest in the biotechnological pursuit of …
osteoarthritis treatment, propelling significant interest in the biotechnological pursuit of …
The sulfation of biomimetic glycosaminoglycan substrates controls binding of growth factors and subsequent neural and glial cell growth
Sulfated glycosaminoglycans (GAGs) are key structural and functional extracellular matrix
(ECM) molecules involved in numerous signaling pathways mainly through their interaction …
(ECM) molecules involved in numerous signaling pathways mainly through their interaction …
Alginate sulfate substrates control growth factor binding and growth of primary neurons: Toward engineered 3D neural networks
Sulfated glycosaminoglycans (sGAGs) are vital molecules of the extracellular matrix (ECM)
of the nervous system known to regulate proliferation, migration, and differentiation of …
of the nervous system known to regulate proliferation, migration, and differentiation of …
Functions of chondroitin/dermatan sulfate containing GalNAc4, 6-disulfate
O Habuchi - Glycobiology, 2022 - academic.oup.com
Chondroitin sulfate (CS) and dermatan sulfate (DS) containing GalNAc4, 6-disulfate
(GalNAc4S6S) were initially discovered in marine animals. Following the discovery, these …
(GalNAc4S6S) were initially discovered in marine animals. Following the discovery, these …
Chondroitin Sulfate Disaccharide Enhances Extracellular Matrix-Related Gene and Protein Expression in Normal Human Dermal Fibroblasts in Vitro
K KITAZAWA, S KANO, F HASHIMOTO… - 日本香粧品学会 …, 2015 - jstage.jst.go.jp
The physiological effects of chondroitin sulfate (CS) depend on the extent of its sulfation.
This study focused on the effects of highly sulfated CS with different molecular weights in …
This study focused on the effects of highly sulfated CS with different molecular weights in …