Cancer-derived exosomes: their role in cancer biology and biomarker development

VC Kok, CC Yu - International Journal of Nanomedicine, 2020 - Taylor & Francis
Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …

Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source

W Meng, C He, Y Hao, L Wang, L Li, G Zhu - Drug delivery, 2020 - Taylor & Francis
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …

[HTML][HTML] Tumor-induced neurogenesis and immune evasion as targets of innovative anti-cancer therapies

RD Cervantes-Villagrana, D Albores-García… - Signal transduction and …, 2020 - nature.com
Normal cells are hijacked by cancer cells forming together heterogeneous tumor masses
immersed in aberrant communication circuits that facilitate tumor growth and dissemination …

The hallmarks of cancer are also the hallmarks of wound healing

L MacCarthy-Morrogh, P Martin - Science Signaling, 2020 - science.org
The Hanahan and Weinberg “hallmarks of cancer” papers provide a useful structure for
considering the various mechanisms driving cancer progression, and the same might be …

[HTML][HTML] Neurobiology of cancer: the role of β-adrenergic receptor signaling in various tumor environments

B Mravec, L Horvathova, L Hunakova - International journal of molecular …, 2020 - mdpi.com
The development and progression of cancer depends on both tumor micro-and
macroenvironments. In addition, psychosocial and spiritual “environments” might also affect …

Tumor innervation: Cancer has some nerve

HD Reavis, HI Chen, R Drapkin - Trends in cancer, 2020 - cell.com
Over the past decade, several landmark reports have demonstrated that the nervous system
plays an active role in cancer initiation and progression. These studies demonstrate that …

Exosomal lncRNA PCAT1 Promotes Tumor Circulating Cell‐Mediated Colorectal Cancer Liver Metastasis by Regulating the Activity of the miR‐329‐3p/Netrin‐1 …

X Fang, Y Xu, K Li, P Liu, H Zhang… - Journal of …, 2022 - Wiley Online Library
Objective. This study explored the colorectal cancer exosome lncRNA prostate cancer
associated transcript 1–(PCAT1) mediated circulating tumors and the mechanism of cell …

HPV+ head and neck cancer–derived small extracellular vesicles communicate with TRPV1+ neurons to mediate cancer pain

KE Inyang, CM Evans, M Heussner, M Petroff… - Pain, 2024 - journals.lww.com
Severe pain is often experienced by patients with head and neck cancer and is associated
with a poor prognosis. Despite its frequency and severity, current treatments fail to …

[HTML][HTML] Cancer-derived exosomes as novel biomarkers in metastatic gastrointestinal cancer

D Zhong, Z Wang, Z Ye, Y Wang, X Cai - Molecular Cancer, 2024 - Springer
Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor
and has a significant impact on mortality rates. Nevertheless, the swift advancement of …

Schwann cells in the tumor microenvironment: Need more attention

L Sun, S Chen, M Chen - Journal of Oncology, 2022 - Wiley Online Library
The tumor microenvironment (TME), which is composed of various cell components and
signaling molecules, plays an important role in the occurrence and progression of tumors …