Philadelphia chromosome–like acute lymphoblastic leukemia

SK Tasian, ML Loh, SP Hunger - Blood, The Journal of the …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as
BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares …

Clinical diagnostics and treatment strategies for Philadelphia chromosome–like acute lymphoblastic leukemia

RC Harvey, SK Tasian - Blood advances, 2020 - ashpublications.org
Philadelphia chromosome-like B-cell acute lymphoblastic leukemia (Ph-like ALL) accounts
for 15% to 30% of B-cell acute lymphoblastic leukemia in older children, adolescents, and …

High frequency and poor outcome of Philadelphia chromosome–like acute lymphoblastic leukemia in adults

KG Roberts, Z Gu, D Payne-Turner… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Philadelphia chromosome (Ph)–like acute lymphoblastic leukemia (ALL) is a high-
risk subtype of childhood ALL characterized by kinase-activating alterations that are …

Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults

N Jain, KG Roberts, E Jabbour, K Patel… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk
subtype of ALL in children. There are conflicting data on the incidence and prognosis of Ph …

Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group

SC Reshmi, RC Harvey, KG Roberts… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk
subtype characterized by genomic alterations that activate cytokine receptor and kinase …

Molecular classification improves risk assessment in adult BCR-ABL1–negative B-ALL

E Paietta, KG Roberts, V Wang, Z Gu… - Blood, The Journal …, 2021 - ashpublications.org
Genomic classification has improved risk assignment of pediatric, but not adult B-lineage
acute lymphoblastic leukemia (B-ALL). The international UKALLXII/ECOG-ACRIN E2993 (# …

Genomic and outcome analyses of Ph-like ALL in NCI standard-risk patients: a report from the Children's Oncology Group

KG Roberts, SC Reshmi, RC Harvey… - Blood, The Journal …, 2018 - ashpublications.org
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL; BCR-ABL1–like
ALL) in children with National Cancer Institute (NCI) intermediate-or high-risk (HR) ALL is …

Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia

SK Tasian, DT Teachey, Y Li, F Shen… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)–like B-cell acute lymphoblastic leukemia (Ph-like ALL) is
associated with activated JAK/STAT, Abelson kinase (ABL), and/or phosphatidylinositol 3 …

[HTML][HTML] Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual …

T Herold, S Schneider, KH Metzeler, M Neumann… - …, 2017 - ncbi.nlm.nih.gov
Philadelphia-like B-cell precursor acute lymphoblastic leukemia (Ph-like ALL) is
characterized by distinct genetic alterations and inferior prognosis in children and younger …

Philadelphia chromosome–like acute lymphoblastic leukemia

CH Pui, KG Roberts, JJ Yang, CG Mullighan - Clinical Lymphoma Myeloma …, 2017 - Elsevier
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a recently
described B-cell precursor ALL with a gene expression profile and a high frequency of IKZF1 …