It is well recognized that the presence of cervical lymph node metastasis is the most
important prognostic factor in oral squamous cell carcinoma (OSCC). In solid epithelial …

Simple Summary Squamous cell carcinoma of the head and neck (SCCHN) is a debilitating
disease that affects hundreds of thousands of individuals worldwide and has a high mortality …

Overall survival remains very poor for patients diagnosed as having head and neck
squamous cell carcinoma (HNSCC). Identification of additional biomarkers and novel …

Background Our previous study demonstrated that aldolase A (ALDOA) is overexpressed in
clinical human lung squamous cell carcinoma and that ALDOA promotes epithelial …

Purpose Evaluate the presence of human papillomavirus (HPV) in biopsies of Brazilian
patients with lung cancer and also the expression of the E6 and E7 oncoproteins. HPV is …

Purpose: Tumor markers that are related to hypoxia, proliferation, DNA damage repair and
stem cell-ness, have a prognostic value in advanced stage HNSCC patients when assessed …

Background: The oncogenic role of epidermal growth factor receptor (EGFR) has been
intensively studied. However, its emerging role in drug resistance has not been fully …

Head and neck squamous cell carcinoma (HNSCC) is highly variable by tumor site,
histologic type, molecular characteristics, and clinical outcome. During recent years …

The therapeutic responses of many solid tumours to chemo-and radio-therapies are far from
fully effective but therapies targeting malignancy-related cellular changes show promise for …

Background and Purpose The penetration of the anaplastic lymphoma kinase (ALK) inhibitor
alectinib in neuroblastomas and the relationship between alectinib and ALK expression are …