Modulating neuroinflammation through molecular, cellular and biomaterial‐based approaches to treat spinal cord injury
The neuroinflammatory response that is elicited after spinal cord injury contributes to both
tissue damage and reparative processes. The complex and dynamic cellular and molecular …
tissue damage and reparative processes. The complex and dynamic cellular and molecular …
Nanoparticle-based delivery to treat spinal cord injury—a mini-review
There is an increasing need to develop improved and non-invasive strategies to treat spinal
cord injury (SCI). Nanoparticles (NPs) are an enabling technology to improve drug delivery …
cord injury (SCI). Nanoparticles (NPs) are an enabling technology to improve drug delivery …
Immunomodulatory nanoparticles mitigate macrophage inflammation via inhibition of PAMP interactions and lactate-mediated functional reprogramming of NF-κB and …
JJM Lasola, AL Cottingham, BL Scotland, N Truong… - Pharmaceutics, 2021 - mdpi.com
Inflammation is a key homeostatic process involved in the body's response to a multitude of
disease states including infection, autoimmune disorders, cancer, and other chronic …
disease states including infection, autoimmune disorders, cancer, and other chronic …
Development of protein–polymer conjugate nanoparticles for modulation of dendritic cell phenotype and Antigen-Specific CD4 T cell responses
BL Scotland, AL Cottingham, JJM Lasola… - ACS Applied Polymer …, 2023 - ACS Publications
Polymeric nanoparticles (NPs) composed of poly (lactic-co-glycolic acid)(PLGA) have found
success in modulating antigen (Ag)-specific T cell responses for the treatment multiple …
success in modulating antigen (Ag)-specific T cell responses for the treatment multiple …
In vivo modulation of angiogenesis and immune response on a collagen matrix via extracorporeal shockwaves
The effective management of tissue integration and immunological responses to transplants
decisively co-determines the success of soft and hard tissue reconstruction. The aim of this …
decisively co-determines the success of soft and hard tissue reconstruction. The aim of this …
Targeting the oxytocinergic system: A possible pharmacological strategy for the treatment of inflammation occurring in different chronic diseases
Unresolved inflammation represents a central feature of different human pathologies
including neuropsychiatric, cardiovascular, and metabolic diseases. The epidemiologic …
including neuropsychiatric, cardiovascular, and metabolic diseases. The epidemiologic …
Hibiscus, rooibos, and yerba mate for healthy aging: A review on the attenuation of in vitro and in vivo markers related to oxidative stress, glycoxidation, and …
The world is currently undergoing a demographic change towards an increasing number of
elderly citizens. Aging is characterized by a temporal decline in physiological capacity, and …
elderly citizens. Aging is characterized by a temporal decline in physiological capacity, and …
[HTML][HTML] Modulatory effects of mushrooms on the inflammatory signaling pathways and pro-inflammatory mediators
A Rowaiye, OI Wilfred, OA Onuh, D Bur, S Oni… - Clinical Complementary …, 2022 - Elsevier
Background Mushrooms include a wide variety of bioactive compounds that have been
linked to therapeutic and nutritional benefits, making them a potential source of new …
linked to therapeutic and nutritional benefits, making them a potential source of new …
Modulating mechanical and shape-memory properties while mitigating degradation-induced inflammation of polylactides by pendant aspirin incorporation
Synergistically modulating mechanical properties and improving shape-memory
performance while mitigating degradation-induced chronic inflammation of polylactide (PLA) …
performance while mitigating degradation-induced chronic inflammation of polylactide (PLA) …
[HTML][HTML] Size, surface charge and flexibility of vinegar-baked Radix Bupleuri polysaccharide affecting the immune response
X Wang, Y Zhao, Y Wu, L Liu, M Liang, M Han… - Arabian Journal of …, 2022 - Elsevier
Remarkably, nanomaterials can interact with the cells of immune system and either enhance
or inhibit its function in many ways. Unfortunately, such valuable information has been …
or inhibit its function in many ways. Unfortunately, such valuable information has been …