Advancing Breast Cancer Diagnosis in 3D: the transformative power of X-ray Phase-Contrast Microtomography for Virtual Histology

S Donato, D Bonazza - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Breast cancer, a prevalent global malignancy in women, demands accurate tissue alteration
detection for effective diagnosis and treatment. Histology, pivotal in diagnosis, faces …

[HTML][HTML] Integrating X-ray phase-contrast imaging and histology for comparative evaluation of breast tissue malignancies in virtual histology analysis

S Donato, LM Arana Peña, F Arfelli, L Brombal… - Scientific Reports, 2024 - nature.com
Detecting breast tissue alterations is essential for cancer diagnosis. However, inherent
bidimensionality limits histological procedures' effectiveness in identifying these changes …

[HTML][HTML] Protocol for 3D virtual histology of unstained human brain tissue using synchrotron radiation phase-contrast microtomography

JY Lee, S Donato, AF Mack, U Mattheus… - Frontiers in …, 2024 - frontiersin.org
X-ray phase-contrast micro computed tomography using synchrotron radiation (SR PhC-
µCT) offers unique 3D imaging capabilities for visualizing microstructure of the human brain …

A comprehensive study of laboratory-based micro-CT for 3D virtual histology of human FFPE tissue blocks

K Tajbakhsh, A Neels, E Fadeeva, JC Larsson… - IEEE …, 2024 - ieeexplore.ieee.org
Advances in laboratory-based X-ray computed tomography (CT) have enabled X-ray 3D
virtual histology. This method shows a great potential as a complementary technique to …

Unveiling tumor invasiveness: enhancing cancer diagnosis with phase-contrast microtomography for 3D virtual histology

S Donato, RG Agostino, LMA Peña, F Arfelli… - … Physical Journal Plus, 2024 - epjplus.epj.org
Malignant diseases are characterized by a critical trait known as invasiveness, where tumor
cells tend to spread from the primary tissue layer into surrounding healthy tissues and …

[HTML][HTML] High-angular-sensitivity X-ray phase-contrast microtomography of soft tissue through a two-directional beam-tracking synchrotron set-up

C Navarrete-León, PS Patrick, A Doherty… - Synchrotron …, 2024 - journals.iucr.org
Two-directional beam-tracking (2DBT) is a method for phase-contrast imaging and
tomography that uses an intensity modulator to structure the X-ray beam into an array of …

[HTML][HTML] Optical clearing: an alternative sample preparation method for propagation based phase contrast CT

MMR Sagar, A Svetlove, L D'Amico… - Frontiers in …, 2024 - frontiersin.org
Synchrotron radiation propagation-based phase-contrast micro-computed tomography (SR
μ CT) has been used increasingly for detailed characterization of tissue specimens …

[HTML][HTML] Mammographically detected breast clustered microcalcifications localized by chest thin-section computed tomography

X Liu, Y Bao, L Sui, J Cao, Y Wang, C Yu… - World Journal of …, 2024 - Springer
Background To explore the capability and clinical significance of chest thin-section
computed tomography (CT) for localization of mammographically detected clustered …

A comprehensive study of micro-CT for 3D virtual histology of FFPE tissue blocks

K Tajbakhsh, A Neels, E Fadeeva, JC Larsson… - Authorea …, 2024 - techrxiv.org
Advances in X-ray computed tomography (CT) has enabled soft-tissue X-ray imaging with
improved contrast and resolution. As a result, non-destructive X-ray 3D virtual histology is …

[PDF][PDF] ESTUDIO DE CALIDAD DE IMAGEN EN TOMOGRAFÍA DE MAMA CON RADIACIÓN DE SINCROTRÓN.

M PEREZ-DÍAZ, L RIGON… - Revista Cubana de …, 2024 - revistacubanadefisica.org
Las imágenes de mamografıa o de tomografıa de mama con rayos-X, utilizando equipos
convencionales, se adquieren en formato 2D o 3D, respectivamente. Estas representan el …