Cell adhesion molecules and their roles and regulation in the immune and tumor microenvironment

H Harjunpää, M Llort Asens, C Guenther… - Frontiers in …, 2019 - frontiersin.org
The immune system and cancer have a complex relationship with the immune system
playing a dual role in tumor development. The effector cells of the immune system can …

β2 Integrins As Regulators of Dendritic Cell, Monocyte, and Macrophage Function

L Schittenhelm, CM Hilkens, VL Morrison - Frontiers in immunology, 2017 - frontiersin.org
Emerging evidence suggests that the β2 integrin family of adhesion molecules have an
important role in suppressing immune activation and inflammation. β2 integrins are …

The kindlin family: functions, signaling properties and implications for human disease

E Rognoni, R Ruppert, R Fässler - Journal of cell science, 2016 - journals.biologists.com
The kindlin (or fermitin) family of proteins comprises three members (kindlin-1,-2 and-3) of
evolutionarily conserved focal adhesion (FA) proteins, whose best-known task is to increase …

Beta2-integrins and interacting proteins in leukocyte trafficking, immune suppression, and immunodeficiency disease

SC Fagerholm, C Guenther, M Llort Asens… - Frontiers in …, 2019 - frontiersin.org
Beta2-integrins are complex leukocyte-specific adhesion molecules that are essential for
leukocyte (eg, neutrophil, lymphocyte) trafficking, as well as for other immunological …

β2 Integrins—multi-functional leukocyte receptors in health and disease

M Bednarczyk, H Stege, S Grabbe, M Bros - International journal of …, 2020 - mdpi.com
β2 integrins are heterodimeric surface receptors composed of a variable α (CD11a-CD11d)
and a constant β (CD18) subunit and are specifically expressed by leukocytes. The α …

Dynamics of the actin cytoskeleton mediates receptor cross talk: An emerging concept in tuning receptor signaling

PK Mattila, FD Batista, B Treanor - Journal of Cell Biology, 2016 - rupress.org
Recent evidence implicates the actin cytoskeleton in the control of receptor signaling. This
may be of particular importance in the context of immune receptors, such as the B cell …

Cationic carbon quantum dots derived from alginate for gene delivery: one-step synthesis and cellular uptake

J Zhou, W Deng, Y Wang, X Cao, J Chen, Q Wang… - Acta biomaterialia, 2016 - Elsevier
Carbon quantum dots (CQDs), unlike semiconductor quantum dots, possess fine
biocompatibility, excellent upconversion properties, high photostability and low toxicity …

Exosomes derived from dental pulp stem cells accelerate cutaneous wound healing by enhancing angiogenesis via the Cdc42/p38 MAPK pathway

Z Zhou, J Zheng, D Lin, R Xu… - … journal of molecular …, 2022 - spandidos-publications.com
Skin wound healing is a common challenging clinical issue which requires advanced
treatment strategies. The present study investigated the therapeutic effects of exosomes …

Nematodes and human therapeutic trials for inflammatory disease

DE Elliott, JV Weinstock - Parasite Immunology, 2017 - Wiley Online Library
Helminth infections likely provide a protective influence against some immune‐mediated
and metabolic diseases because helminth infection dramatically decreased in developed …

The interplay between integrins and immune cells as a regulator in cancer immunology

Q Zhang, S Zhang, J Chen, Z Xie - International Journal of Molecular …, 2023 - mdpi.com
Integrins are a group of heterodimers consisting of α and β subunits that mediate a variety of
physiological activities of immune cells, including cell migration, adhesion, proliferation …