Pulmonary toxicants and fibrosis: innate and adaptive immune mechanisms
Pulmonary fibrosis is characterized by destruction and remodeling of the lung due to an
accumulation of collagen and other extracellular matrix components in the tissue. This …
accumulation of collagen and other extracellular matrix components in the tissue. This …
Disease‐modifying treatment of chemical threat agent–induced acute lung injury
Acute respiratory distress syndrome (ARDS) is a highly morbid lung pathology induced by
exposure to chemical warfare agents, including vesicants, phosgene, chlorine, and ricin. In …
exposure to chemical warfare agents, including vesicants, phosgene, chlorine, and ricin. In …
Acute intensive care unit management of mustard gas victims: the Turkish experience
E Kilic, M Ortatatli, S Sezigen, RK Eyison… - Cutaneous and ocular …, 2018 - Taylor & Francis
Purpose: Sulphur mustard (SM) is an highly toxic and vesicant chemical weapon that was
used in various military conflicts several times in the history. The severity of ocular, dermal …
used in various military conflicts several times in the history. The severity of ocular, dermal …
Acute corneal injury in rabbits following nitrogen mustard ocular exposure
DG Goswami, R Kant, DA Ammar, D Kumar… - … and molecular pathology, 2019 - Elsevier
Sulfur mustard (SM), a potent vesicating chemical warfare agent, and its analog nitrogen
mustard (NM), are both strong bi-functional alkylating agents. Eyes, skin, and the respiratory …
mustard (NM), are both strong bi-functional alkylating agents. Eyes, skin, and the respiratory …
Progressive lung injury, inflammation, and fibrosis in rats following inhalation of sulfur mustard
R Malaviya, EV Abramova, RC Rancourt… - Toxicological …, 2020 - academic.oup.com
Sulfur mustard (SM) inhalation causes debilitating pulmonary injury in humans which
progresses to fibrosis. Herein, we developed a rat model of SM toxicity which parallels …
progresses to fibrosis. Herein, we developed a rat model of SM toxicity which parallels …
An Official American Thoracic Society Workshop Report: chemical inhalational disasters. Biology of lung injury, development of novel therapeutics, and medical …
This report is based on the proceedings from the Inhalational Lung Injury Workshop jointly
sponsored by the American Thoracic Society (ATS) and the National Institutes of Health …
sponsored by the American Thoracic Society (ATS) and the National Institutes of Health …
Mustard vesicant-induced lung injury: Advances in therapy
B Weinberger, R Malaviya, VR Sunil, A Venosa… - Toxicology and applied …, 2016 - Elsevier
Most mortality and morbidity following exposure to vesicants such as sulfur mustard is due to
pulmonary toxicity. Acute injury is characterized by epithelial detachment and necrosis in the …
pulmonary toxicity. Acute injury is characterized by epithelial detachment and necrosis in the …
Advances in treatment of acute sulfur mustard poisoning–a critical review
L Etemad, M Moshiri, M Balali-Mood - Critical reviews in toxicology, 2019 - Taylor & Francis
Sulfur mustard (SM) is a blistering chemical warfare agent that was used during the World
War I and in the Iraq–Iran conflict. The aim of this paper is to discuss and critically review the …
War I and in the Iraq–Iran conflict. The aim of this paper is to discuss and critically review the …
Bronchiolitis obliterans and pulmonary fibrosis after sulfur mustard inhalation in rats
MD McGraw, MM Dysart, TB Hendry-Hofer… - American Journal of …, 2018 - atsjournals.org
Inhalation of powerful chemical agents, such as sulfur mustard (SM), can have debilitating
pulmonary consequences, such as bronchiolitis obliterans (BO) and parenchymal fibrosis …
pulmonary consequences, such as bronchiolitis obliterans (BO) and parenchymal fibrosis …
TRPA1 and CGRP antagonists counteract vesicant-induced skin injury and inflammation
S Achanta, NR Chintagari, M Brackmann… - Toxicology letters, 2018 - Elsevier
The skin is highly sensitive to the chemical warfare agent in mustard gas, sulfur mustard
(SM) that initiates a delayed injury response characterized by erythema, inflammation and …
(SM) that initiates a delayed injury response characterized by erythema, inflammation and …