Background Animal and human studies highlight the role of oxytocin in social cognition and
behavior and the potential of intranasal oxytocin (IN-OT) to treat social impairment in …

Accumulating evidence demonstrates the important role of oxytocin (OT) in the modulation of
social cognition and behavior. This has led many to suggest that the intranasal …

Deficits in social cognition are pervasive and characteristic of neurodevelopmental disorders
(NDDs). Clinical trials of intranasal oxytocin (IN-OT) to improve social cognition have yielded …

Current evidence-based pharmacotherapy options in children with ASD are very limited, and
many have substantial adverse events. Clinicians should use pharmacotherapy as a part of …

Social decisions require evaluation of costs and benefits to oneself and others. Long
associated with emotion and vigilance, the amygdala has recently been implicated in both …

The prosocial neuropeptide oxytocin is being developed as a potential treatment for various
neuropsychiatric disorders including autism spectrum disorder (ASD). Early studies using …

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder
associated with both genetic and environmental risks. Neuroimaging approaches have been …

Oxytocin (OT) has become a focus in investigations of autism spectrum disorder (ASD). The
social deficits that characterize ASD may relate to reduced connectivity between brain sites …

The neuropeptide oxytocin has been in the focus of scientists for decades due to its
profound and pleiotropic effects on physiology, activity of neuronal circuits and behaviors …

Across many mammalian species there exist genetic and biological systems that facilitate
the tendency to be social. Oxytocin is a neuropeptide involved in social-approach behaviors …