Throughout the body, T cells monitor MHC-bound ligands expressed on the surface of
essentially all cell types. MHC ligands that trigger a T cell immune response are referred to …

Human leukocyte antigens (HLA) are cell-surface proteins that present peptides to T cells.
These peptides are bound within the peptide binding cleft of HLA, and together as a …

Background MHC class II binding predictions are widely used to identify epitope candidates
in infectious agents, allergens, cancer and autoantigens. The vast majority of prediction …

The identification of MHC class II restricted peptide epitopes is an important goal in
immunological research. A number of computational tools have been developed for this …

In this study a systematic attempt has been made to integrate various approaches in order to
predict allergenic proteins with high accuracy. The dataset used for testing and training …

Background Class I major histocompatibility complex (MHC) molecules bind, and present to
T cells, short peptides derived from intracellular processing of proteins. The peptide …

ProPred1 is an on-line web tool for the prediction of peptide binding to MHC class-I alleles.
This is a matrix-based method that allows the prediction of MHC binding sites in an antigenic …

Cancer immunotherapy has an outstanding position in cancer prevention and treatment. In
this kind of therapy, the immune system is activated to eliminate cancerous cells. Multi …

Cytotoxic T lymphocyte (CTL) epitopes are potential candidates for subunit vaccine design
for various diseases. Most of the existing T cell epitope prediction methods are indirect …

Abstract SATPdb (http://crdd. osdd. net/raghava/satpdb/) is a database of structurally
annotated therapeutic peptides, curated from 22 public domain peptide databases/datasets …