Background Development of efficient strategies has always been one of the great
perspectives for biotechnologists. During the last decade, genome editing of different …

Skin injuries and chronic non-healing wounds are one of the major global burdens on the
healthcare systems worldwide due to their difficult-to-treat nature, associated co-morbidities …

Livestock is an essential life commodity in modern agriculture involving breeding and
maintenance. The farming practices have evolved mainly over the last century for …

Breast cancer (BC) is the most prevalent malignancy and the second leading cause of death
among women worldwide that is caused by numerous genetic and environmental factors …

Pain and its alleviation are currently a highly studied issue in human health. Research on
pain and response to analgesia has evolved to include the effects of genetics, heritability …

Polyglutamine spinocerebellar ataxias (SCAs) comprise a heterogeneous group of six
autosomal dominant ataxias caused by cytosine–adenine–guanine repeat expansions in …

Polyglutamine spinocerebellar ataxias (PolyQ SCAs) are a group of 6 rare autosomal
dominant diseases, which arise from an abnormal CAG repeat expansion in the coding …

The pathogenesis of neurodegenerative diseases (NDDs) is complex and diverse. Over the
decades, our understanding of NDD has been limited to pathological features. However …

In the past two decades, genome editing has proven its value as a powerful tool for
modeling or even treating numerous diseases. After the development of protein-guided …

基因编辑是一项旨在对基因组进行定点修饰的新技术, 为基因功能分析提供了更强大的工具.
现在研究人员可以很容易地利用锌指核酸酶(zinc-finger nuclease, ZFN) …