[HTML][HTML] Gut microbiome and health: mechanistic insights

WM De Vos, H Tilg, M Van Hul, PD Cani - Gut, 2022 - gut.bmj.com
The gut microbiota is now considered as one of the key elements contributing to the
regulation of host health. Virtually all our body sites are colonised by microbes suggesting …

The gut microbiota in obesity and weight management: microbes as friends or foe?

M Van Hul, PD Cani - Nature Reviews Endocrinology, 2023 - nature.com
Obesity is caused by a long-term difference between energy intake and expenditure—an
imbalance that is seemingly easily restored by increasing exercise and reducing caloric …

A mechanism by which gut microbiota elevates permeability and inflammation in obese/diabetic mice and human gut

SP Mishra, B Wang, S Jain, J Ding, J Rejeski… - Gut, 2023 - gut.bmj.com
Objective Ample evidence exists for the role of abnormal gut microbiota composition and
increased gut permeability ('leaky gut') in chronic inflammation that commonly co-occurs in …

The postprandial actions of GLP-1 receptor agonists: the missing link for cardiovascular and kidney protection in type 2 diabetes

MC Thomas, MT Coughlan, ME Cooper - Cell Metabolism, 2023 - cell.com
Recent clinical trials in people with type 2 diabetes have demonstrated beneficial actions on
heart and kidney outcomes following treatment with GLP-1RAs. In part, these actions are …

[HTML][HTML] Pinostrobin ameliorates lipopolysaccharide (LPS)-induced inflammation and endotoxemia by inhibiting LPS binding to the TLR4/MD2 complex

AMGK Athapaththu, KT Lee, MHD Kavinda… - Biomedicine & …, 2022 - Elsevier
Pinostrobin is a natural flavonoid with valuable pharmacological properties, including anti-
cancer, anti-viral, and anti-oxidant activities. However, the anti-inflammatory effects of …

Gut microbiota bridges dietary nutrients and host immunity

L Fan, Y Xia, Y Wang, D Han, Y Liu, J Li, J Fu… - Science China Life …, 2023 - Springer
Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and
entrain each other, and thus affect host health and immune-mediated diseases. Here, we …

Gut microbiota composition in prediabetes and newly diagnosed type 2 diabetes: a systematic review of observational studies

G Letchumanan, N Abdullah, M Marlini… - Frontiers in cellular …, 2022 - frontiersin.org
Evidence of gut microbiota involvement in regulating glucose metabolism and type 2
diabetes mellitus (T2DM) progression is accumulating. The understanding of microbial …

Cranberry polyphenols and agave agavins impact gut immune response and microbiota composition while improving gut barrier function, inflammation, and glucose …

AS Medina-Larqué, MC Rodríguez-Daza… - Frontiers in …, 2022 - frontiersin.org
The consumption of plant-based bioactive compounds modulates the gut microbiota and
interacts with the innate and adaptive immune responses associated with metabolic …

The role of the gut microbiota in health and cardiovascular diseases

L Wang, S Wang, Q Zhang, C He, C Fu, Q Wei - Molecular biomedicine, 2022 - Springer
The gut microbiota is critical to human health, such as digesting nutrients, forming the
intestinal epithelial barrier, regulating immune function, producing vitamins and hormones …

Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation

Y Qi, J He, Y Zhang, Q Ge, Q Wang, L Chen… - Nature …, 2023 - nature.com
Declined numbers and weakened functions of intestinal stem cells (ISCs) impair the integrity
of the intestinal epithelium during aging. However, the impact of intestinal microbiota on …