Simple Summary Drug resistance remains one of the major problems in cancer therapy and
is responsible for up to 90% of cancer-related deaths. It exists across all types of cancer and …

Cancer immunotherapy, which reactivates weakened immune cells of cancer patients, has
yielded great success in recent years. Among immunotherapeutic agents, immune …

Abstract The PI3K/AKT signaling has crucial role in the regulation of numerous physiological
functions through activation of downstream effectors and modulation of cell cycle transition …

Free radicals contain one or more unpaired electrons in their valence shell, thus making
them unstable, short-lived, and highly reactive species. Excessive generation of these free …

Abstract Phosphoinositide-3 kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)
signaling pathway is one of the most important proliferative signaling pathways with critical …

Cholesterol/sphingolipid-rich membrane domains, known as lipid rafts or membrane rafts,
play a critical role in the compartmentalization of signaling pathways. Physical segregation …

Selenium is an essential trace element that is crucial for cellular antioxidant defense against
reactive oxygen species (ROS). Recently, many selenium-containing compounds have …

Photobiomodulation (PBM) imparts therapeutically significant benefits in the healing of
chronic wounds. Chronic wounds develop when the stages of wound healing fail to progress …

Gliomas are the most lethal primary brain tumors in adults. These highly invasive tumors
have poor 5-year survival for patients. Gliomas are principally characterized by rapid …

Cervical Cancer is one of the leading causes of cancer‑associated mortality in women. The
present study aimed to identify key genes and pathways involved in cervical cancer (CC) …