Positron emission tomography (PET) provides three-dimensional images of the distributions
of radionuclides that have been inhaled or injected into the lungs. By using radionuclides …

Infectious and inflammatory pulmonary diseases are a leading cause of morbidity and
mortality worldwide. Although infrequently used in this setting, molecular imaging may …

Background Airway inflammation plays a critical role in the progression of cystic fibrosis (CF)
lung disease, and in the destruction of airways and lung parenchyma. Current methods to …

Methods currently used to assess lung and airway inflammation are often poorly
quantitative, invasive, nonspecific, or insensitive. Positron emission tomography (PET) with …

Background Pseudomonas aeruginosa (PA) and Burkholderia cepacia complex (Bcc),
commonly found in the lungs of cystic fibrosis (CF) patients, often produce cyanide (CN) …

This study was to evaluate whether macrophage migration inhibitory factor (MIF) can be
used as a better marker of inflammatory detection through the biodistribution and …

The possibility and promise of being able to follow the expression of biology modifying
genes noninvasively in whole animals, including humans, is one of the most exciting …

Cystic brosis (CF) lung disease is predominantly a consequence of destruction of the
airways, which causes bronchiectasis and bronchiolectasis. Conventionally, treatment …

Over the past 20 years, as clinical applications have been gradually expanding, positron
emission tomography (PET) has become an indispensable imaging technique in several …

Selective expression of therapeutic genes in tissues of interest is an essential requirement in
gene therapy applications. This is due to the adverse effects of therapeutic genes on normal …