Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Background Cepharanthine (CEP) is a drug used in Japan since the 1950s to treat a
number of acute and chronic diseases, including treatment of leukopenia, snake bites …

Cadmium (Cd) is a heavy metal toxicant as a common pollutant derived from many
agricultural and industrial sources. The absorption of Cd takes place primarily through Cd …

Lidocaine is an amide-class local anesthetic used clinically to inhibit pain sensations.
Systemic administration of lidocaine has antinociceptive, antiarrhythmic, anti-inflammatory …

Bone regeneration is a complex and well‐coordinated process that involves crosstalk
between immune cells and resident cells in the injury site. Transplantation of mesenchymal …

Abstract Background Mesenchymal stem cells (MSCs) are capable of immunomodulation
and tissue regeneration, highlighting their potential translational application for treating …

Osteoporosis is characterized by a decrease in bone mass and strength, rendering people
prone to osteoporotic fractures caused by low-energy forces. The primary treatment strategy …

Aberrant macrophage activation during intracellular infection generates immunopathologies
that can cause severe human morbidity. A better understanding of immune subversion …

Inflammation, an essential tissue response to extrinsic/intrinsic damage, is a very dynamic
process in terms of complexity and extension of cellular and metabolic involvement. The aim …

Osteoporosis is currently the most prevalent bone disorder worldwide and is characterized
by low bone mineral density and an overall increased risk of fractures. To treat osteoporosis …