Heat has been used to treat tumors for thousands of years. There are reports of the
Egyptians and Greek philosophers using such treatments as far back as 3000 BC and 500 …

Telomeres are located at the ends of all eukaryotic chromosomes and protect them from
deleterious events such as inappropriate DNA repair, illegitimate recombination or improper …

Genomes are inherently unstable and require constant DNA repair to maintain their genetic
information. However, selective pressure has optimized repair mechanisms in somatic cells …

The objective of the cross-sectional study was to assess whether exposure to polycyclic
aromatic hydrocarbons (PAHs) from coke oven emissions contributed to alteration of semen …

Carrier of genetic instructions used in development, functioning and reproduction of all
leaving organisms is a macromolecule called DNA. Alteration in chemical structure of DNA …

A main assumption of molecular population genetics is that genomic mutation rate does not
depend on sequence function. Challenging this assumption, a recent study has found a …

Anticancer drugs, such as alkylating agents, can affect male fertility by targeting the DNA of
proliferative spermatogonial stem cells (SSC). Therefore, to reduce such side effects, other …

Spermatogenic arrest is a severe form of non-obstructive azoospermia (NOA), which occurs
in 10–15% of infertile men. Interruption in spermatogenic progression at premeiotic, meiotic …

A complex regulatory network of signaling pathways safeguards genome integrity following
DNA damage. When double strand breaks occur several enzymes and mediators are …

Research on the mechanisms of reproductive toxicity caused by persistent organic
pollutants (POPs) in marine animals has received significant attention. One group of typical …