[HTML][HTML] The hidden power of secondary metabolites in plant-fungi interactions and sustainable phytoremediation

NA Elhamouly, OA Hewedy, A Zaitoon… - Frontiers in Plant …, 2022 - frontiersin.org
The global environment is dominated by various small exotic substances, known as
secondary metabolites, produced by plants and microorganisms. Plants and fungi are …

[HTML][HTML] The Role of Host and Fungal Factors in the Commensal-to-Pathogen Transition of Candida albicans

ID Jacobsen - Current Clinical Microbiology Reports, 2023 - Springer
Abstract Purpose of Review The fungus Candida albicans has evolved to live in close
association with warm-blooded hosts and is found frequently on mucosal surfaces of healthy …

[HTML][HTML] NLRP3 Inflammasome-Mediated Pyroptosis Pathway Contributes to the Pathogenesis of Candida albicans Keratitis

H Lian, XL Fang, Q Li, S Liu, Q Wei, X Hua, W Li… - Frontiers in …, 2022 - frontiersin.org
Purpose Fungal keratitis is a sight-threatening corneal infection caused by fungal
pathogens, and the pathogenic mechanisms have not been fully elucidated. The aim of this …

[HTML][HTML] “Under Pressure”–How fungi evade, exploit, and modulate cells of the innate immune system

T Lange, L Kasper, MS Gresnigt, S Brunke… - Seminars in Immunology, 2023 - Elsevier
The human immune system uses an arsenal of effector mechanisms to prevent and
counteract infections. Yet, some fungal species are extremely successful as human …

Dimethyl fumarate ameliorates fungal keratitis by limiting fungal growth and inhibiting pyroptosis

L Gu, J Lin, Q Wang, L Zhang, M Yin, H Lin… - International …, 2023 - Elsevier
Purpose We aimed to investigate the therapeutic role of dimethyl fumarate (DMF) in fungal
keratitis. Methods Human corneal epithelial cells (HCECs) and mouse models of fungal …

“We've got to get out”—Strategies of human pathogenic fungi to escape from phagocytes

J Sonnberger, L Kasper, T Lange… - Molecular …, 2024 - Wiley Online Library
Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …

[HTML][HTML] Melanin depletion affects Aspergillus flavus conidial surface proteins, architecture, and virulence

O Rudhra, H Gnanam, S Sivaperumal… - Applied Microbiology …, 2024 - Springer
Melanin is an Aspergillus flavus cell wall component that provides chemical and physical
protection to the organism. However, the molecular and biological mechanisms modulating …

[HTML][HTML] The Changes in Mitochondrial Morphology and Physiology Accompanying Apoptosis in Galleria mellonella (Lepidoptera) Immunocompetent Cells during …

A Kaczmarek, AK Wrońska, MI Boguś - International Journal of Molecular …, 2023 - mdpi.com
Mitochondria have been shown to play an important role in apoptosis using mammalian cell
lines. However, their role in insects is not fully understood; thus, more indepth studies of …

The secretory Candida effector Sce1 licenses fungal virulence by masking the immunogenic β‐1,3‐glucan and promoting apoptosis of the host cells

H Wu, L Wang, W Wang, Z Shao, XM Jia, H Xiao… - Mlife, 2023 - Wiley Online Library
Candida albicans deploys a variety of mechanisms such as morphological switch and
elicitor release to promote virulence. However, the intricate interactions between the fungus …

Biomolecular activity of cryptococcus during cryptococcosis: A review of molecular interactions of cryptococcus with human immune system and blood-brain-barrier

J Julian, R Adawiyah, S Wahdini - African Journal of Infectious Diseases, 2024 - ajol.info
Global mycosis is still a problem. One of these is the cryptococcal disease. A systemic
mycosis brought on by Cryptococcus is called cryptococcosis. Host immunological …