Abstract Machine learning is becoming an integral part of the Design-Build-Test-Learn cycle
in biotechnology. Machine learning models learn from collected datasets such as omics data …

Today's environmental balance has been compromised by the unreasonable and
sometimes dangerous actions committed by humans to maintain their dominance over the …

Food enzymes are basic components used for food processing. Through catalysis, food
enzymes can function as removing allergy, enriching absorbable nutrients, improving food …

Assigning or proposing a catalysing enzyme given a chemical or biochemical reaction is of
great interest to life sciences and chemistry alike. The exploration and design of metabolic …

蛋白质工程是合成生物学领域的重要研究方向之一. 但目前人类对于蛋白质折叠,
酶天然进化机制等基础生物学问题的理解仍很有限, 因此基于理性设计方法进行蛋白质的功能 …

Motivation As experimental efforts are costly and time consuming, computational
characterization of enzyme capabilities is an attractive alternative. We present and evaluate …

Microbial cell factories (MCFs) have been leveraged to construct sustainable platforms for
value-added compound production. To optimize metabolism and reach optimal productivity …

Classifying proteins into their respective enzyme class is an interesting question for
researchers for a variety of reasons. The open source Protein Data Bank (PDB) contains …

Motivation With the development of sequencing techniques, the discovery of new proteins
significantly exceeds the human capacity and resources for experimentally characterizing …

The rapid expansion of protein sequence and structure databases has resulted in a
significant number of proteins with ambiguous or unknown function. While advances in …