Therapeutic potential of plant-derived tannins in non-malignant respiratory diseases
Respiratory diseases are the major cause of human illness and death around the world.
Despite advances in detection and treatment, very few classes of safe and effective therapy …
Despite advances in detection and treatment, very few classes of safe and effective therapy …
Evolution of natural product scaffolds as potential proteasome inhibitors in developing cancer therapeutics
Homeostasis between protein synthesis and degradation is a critical biological function
involving a lot of precise and intricate regulatory systems. The ubiquitin-proteasome …
involving a lot of precise and intricate regulatory systems. The ubiquitin-proteasome …
Epigallocatechin-3-Gallate (EGCG), an active compound of green tea attenuates acute lung injury regulating macrophage polarization and Krüpple-like-factor 4 (KLF4 …
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are serious clinical
complications with a high frequency of morbidity and mortality. The initiation and …
complications with a high frequency of morbidity and mortality. The initiation and …
The medicinal value of tea drinking in the management of COVID-19
J Ge, T Song, M Li, W Chen, J Li, S Gong, Y Zhao, L Ma… - Heliyon, 2023 - cell.com
Abstract Corona Virus Disease 2019 (COVID-19) is presently the largest international public
health event, individuals infected by the virus not only have symptoms such as fever, dry …
health event, individuals infected by the virus not only have symptoms such as fever, dry …
[HTML][HTML] Monomeric compounds from traditional Chinese medicine: New hopes for drug discovery in pulmonary fibrosis
Q Wang, W Li, H Hu, X Lu, S Qin - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Pulmonary fibrosis (PF) is a chronic and irreversible pulmonary disease, and can lead to
decreased lung function, respiratory failure and even death. The pathogenesis research and …
decreased lung function, respiratory failure and even death. The pathogenesis research and …
(-)-epigallocatechin 3-gallate protects pancreatic β-cell against excessive autophagy-induced injury through promoting FTO degradation
Y Shao, Y Zhang, S Zou, J Wang, X Li, M Qin, L Sun… - Autophagy, 2024 - Taylor & Francis
Excessive macroautophagy/autophagy leads to pancreatic β-cell failure that contributes to
the development of diabetes. Our previous study proved that the occurrence of deleterious …
the development of diabetes. Our previous study proved that the occurrence of deleterious …
Natural products are an important source for proteasome regulating agents
P An, LJ Zhang, W Peng, YY Chen, QP Liu, X Luan… - Phytomedicine, 2021 - Elsevier
Background Natural medicines have a long history in the prevention and treatment of
various diseases in East Asian region, especially in China. Modern research has proved that …
various diseases in East Asian region, especially in China. Modern research has proved that …
Flavor perception and health benefits of tea
J Yu, K Zhang, Y Wang, X Zhai, X Wan - Advances in Food and Nutrition …, 2023 - Elsevier
As one of the most consumed non-alcoholic beverages in the world, tea is acclaimed for its
pleasant flavor and various health benefits. Different types of tea present a distinctive flavor …
pleasant flavor and various health benefits. Different types of tea present a distinctive flavor …
Neurodegenerative Proteinopathies Induced by Environmental Pollutants: Heat Shock Proteins and Proteasome as Promising Therapeutic Tools
Environmental pollutants'(EPs) amount and diversity have increased in recent years due to
anthropogenic activity. Several neurodegenerative diseases (NDs) are theorized to be …
anthropogenic activity. Several neurodegenerative diseases (NDs) are theorized to be …
Epigallocatechine-3-gallate inhibits the adipogenesis of human mesenchymal stem cells via the regulation of protein phosphatase-2A and myosin phosphatase
Epigallocatechin-3-gallate (EGCG) has widespread effects on adipocyte development.
However, the molecular mechanisms of EGCG are not fully understood. We investigate the …
However, the molecular mechanisms of EGCG are not fully understood. We investigate the …