Endothelin system in hypertension and chronic kidney disease

EL Schiffrin, DM Pollock - Hypertension, 2024 - Am Heart Assoc
ET (endothelin) is a powerful vasoconstrictor 21-amino acid peptide present in many tissues,
which exerts many physiological functions across the body and participates as a mediator in …

Non-HLA antibodies in kidney transplantation: Immunity and genetic insights

BM Sorohan, C Baston, D Tacu, C Bucșa, C Țincu… - Biomedicines, 2022 - mdpi.com
The polymorphic human leukocyte antigen (HLA) system has been considered the main
target for alloimmunity, but the non-HLA antibodies and autoimmunity have gained …

Non-HLA antibodies in hand transplant recipients are connected to multiple acute rejection episodes and endothelial activation

D Sikorska, D Kamińska, R Catar, M Banasik… - Journal of Clinical …, 2022 - mdpi.com
The role of anti-HLA antibodies in transplant rejection is well-known but the injury
associated with non-HLA antibodies is now widely discussed. The aim of our study was to …

Levels of angiotensin II type-1 receptor antibodies and endothelin-1 type-A receptor antibodies correlate with antibody-mediated rejection and poor graft function in …

C Liu, ZY Kang, Z Yin, Y Xiao, W Liu, Y Zhao… - Transplant Immunology, 2022 - Elsevier
Objective Angiotensin II type-1 receptor antibodies (AT1R-Ab) and endothelin-1 type-A
receptor antibodies (ETAR-Ab) are non-human leukocyte antigen (HLA) antibodies that can …

Impact of everolimus plus calcineurin inhibitor on formation of non-HLA antibodies and graft outcomes in kidney transplant recipients: 12-month results from the …

A Philippe, W Arns, V Ditt, IA Hauser… - Frontiers in …, 2023 - frontiersin.org
Background Non-human leukocyte antigen (non-HLA) antibodies including antibodies
targeting Angiotensin II type 1 (AT1R) and Endothelin-1 type A (ETAR) receptors represent a …

Chronic Active T-Cell Mediated Kidney Rejection as a Clinically Significant Type of Allograft Loss?

J Mizera, J Pilch, D Kamińska, M Krajewska, P Donizy… - Diagnostics, 2022 - mdpi.com
The purpose of this article is to assess the present knowledge about chronic active (CA) T-
cell mediated rejection (TCMR) of a kidney. In the research authors review current Banff …

Significance of indoleamine 2, 3-dioxygenase expression in the immunological response of kidney graft recipients

K Wiśnicki, P Donizy, A Remiorz, D Janczak… - Diagnostics, 2022 - mdpi.com
Kidney transplantation is unquestionably the most advantageous and preferred treatment
when patients with end-stage renal disease are considered. It does have a substantially …

Therapy in the Course of Kidney Graft Rejection—Implications for the Cardiovascular System—A Systematic Review

J Mizera, J Pilch, U Giordano, M Krajewska, M Banasik - Life, 2023 - mdpi.com
Kidney graft failure is not a homogenous disease and the Banff classification distinguishes
several types of graft rejection. The maintenance of a transplant and the treatment of its …

[HTML][HTML] Exploration of the shared gene signatures and biological mechanisms between ischemia-reperfusion injury and antibody-mediated rejection in renal …

S Jiang, H Su - Transplant Immunology, 2024 - Elsevier
Background Antibody-mediated rejection (ABMR) plays a crucial role in graft loss during
allogeneic renal transplantation. In renal transplantation, ischemia-reperfusion injury (IRI) is …

Association between anti‐endothelial antigen antibodies and allograft rejection in kidney transplantation

HJ Lee, KH Shin, IY Kim, BH Choi… - Journal of Clinical …, 2023 - Wiley Online Library
Background Endothelial cells are vital in the transplant immune system as semiprofessional
antigen‐presenting cells. Few studies have investigated the importance of anti‐endothelin …