[HTML][HTML] The prognostic utility of protein C as a biomarker for adult sepsis: a systematic review and meta-analysis

V Catenacci, F Sheikh, K Patel, AE Fox-Robichaud - Critical Care, 2022 - Springer
Background Sepsis, the dysregulated host response to infection, triggers abnormal pro-
coagulant and pro-inflammatory host responses. Limitations in early disease intervention …

Update on the role of endothelial cells in trauma

J Greven, R Pfeifer, Q Zhi, HC Pape - European Journal of Trauma and …, 2018 - Springer
Purpose This review gives an overview of physiological processes, mainly regarding
vascular endothelial cells and their important role in hemostasis, information processing …

The protein C pathway and sepsis

P Della Valle, G Pavani, A D'Angelo - Thrombosis research, 2012 - Elsevier
After the discovery of the key components of the protein C (PC) pathway a beneficial effect
on survival of the infusion of activated protein C (APC) in animal models of sepsis was …

Is EPCR a multi-ligand receptor? Pros and cons

R Montes, C Puy, E Molina… - Thrombosis and …, 2012 - thieme-connect.com
In the last decade, the endothelial cell protein C/activated protein C receptor (EPCR) has
received considerable attention. The role initially attributed to EPCR, ie the enhancement of …

[HTML][HTML] Thrombomodulin induces anti-inflammatory effects by inhibiting the rolling adhesion of leukocytes in vivo

S Nishizawa, J Kikuta, S Seno, M Kajiki… - Journal of …, 2020 - Elsevier
Thrombomodulin (TM) is an integral membrane protein expressed on the surface of vascular
endothelial cells that suppresses blood coagulation. Recent studies have shown that TM …

Dystrophin deficiency promotes leukocyte recruitment in mdx mice

SA Kranig, R Tschada, M Braun, C Patry, J Pöschl… - Pediatric …, 2019 - nature.com
Background A growing body of evidence defines inflammation as a hallmark feature of
disease pathogenesis of Duchenne muscular dystrophy. To tailor potential immune …

[HTML][HTML] Ovocalyxin-36 is an effector protein modulating the production of proinflammatory mediators

J Kovacs-Nolan, C Cordeiro, D Young, Y Mine… - Veterinary Immunology …, 2014 - Elsevier
Sepsis is a systemic inflammatory response syndrome during infection. Therapeutic agents
are essential to protect the host from sepsis. Ovocalyxin-36 (OCX-36) is a chicken eggshell …

The protein C pathway in cancer metastasis

CA Spek, VR Arruda - Thrombosis research, 2012 - Elsevier
Cancer is frequently associated with activation of blood coagulation, which in turn has been
suggested to promote tumor growth and metastasis. Indeed, low molecular weight heparin …

[PDF][PDF] ST 段抬高型心肌梗死患者循环微RNA-92a 表达的研究

王虹, 林英忠, 陆红梅, 周莹, 罗程, 陆山河, 赵林… - 2011 - cccm-em120.com
[111 要] 目66 了解横RNA_626 (66iR_626) 在ST 段抬高型心肌粳死僵扭MD
滨生发展中的表达. 21. 及轻皮冠状动脉介人治疗使矶) 对循环666-62666 达的影响, 探讨血6 …

Diet-induced obesity reprograms the inflammatory response of the murine lung to inhaled endotoxin

SC Tilton, KM Waters, NJ Karin… - Toxicology and applied …, 2013 - Elsevier
The co-occurrence of environmental factors is common in complex human diseases and, as
such, understanding the molecular responses involved is essential to determine risk and …