Cystic fibrosis–related liver disease: research challenges and future perspectives

D Debray, MR Narkewicz, FAJA Bodewes… - Journal of pediatric …, 2017 - journals.lww.com
Objectives: Hepatobiliary complications are a leading cause of morbidity and mortality in
cystic fibrosis (CF) patients. Knowledge of the underlying pathological aspects and optimal …

Transient elastography for the diagnosis of liver fibrosis

V De LéDinghen, J Vergniol - Expert review of medical devices, 2010 - Taylor & Francis
Transient elastography (FibroScan®) is a noninvasive method proposed for the assessment
of liver fibrosis in patients with chronic liver diseases by measuring liver stiffness. It can be …

Healthcare cost and utilization in nonalcoholic fatty liver disease: real‐world data from a large US claims database

AM Allen, HK Van Houten, LR Sangaralingham… - Hepatology, 2018 - journals.lww.com
Cystic fibrosis (CF)‐associated liver disease (CFLD) is a hepatobiliary complication of CF.
Current diagnostic modalities rely on nonspecific assessments, whereas liver biopsy is the …

Evaluation of cervical stiffness during pregnancy using semiquantitative ultrasound elastography

E Hernandez‐Andrade, SS Hassan… - … in Obstetrics & …, 2013 - Wiley Online Library
Objective To evaluate cervical stiffness during pregnancy using ultrasound‐derived
elastography, a method used to estimate the average tissue displacement (strain) within a …

[PDF][PDF] Adult‐onset cystic fibrosis liver disease: diagnosis and characterization of an underappreciated entity

C Koh, S Sakiani, P Surana, X Zhao, J Eccleston… - …, 2017 - Wiley Online Library
Cystic fibrosis (CF) liver disease (CFLD), a leading cause of death in CF, is mostly described
in pediatric populations. Adult‐onset CFLD lacks sufficient characterization and diagnostic …

[PDF][PDF] Increased hepatic stiffness as consequence of high hepatic afterload in the Fontan circulation: a vascular Doppler and elastography study

SS Kutty, Q Peng, DA Danford, SE Fletcher… - …, 2014 - Wiley Online Library
Hepatic dysfunction is a recognized complication after Fontan palliation of congenital heart
disease. We sought to quantitatively measure hepatic stiffness and vascular Doppler indices …

[PDF][PDF] Aspartate aminotransferase to platelet ratio and fibrosis‐4 as biomarkers in biopsy‐validated pediatric cystic fibrosis liver disease

DH Leung, M Khan, CG Minard, D Guffey… - …, 2015 - Wiley Online Library
Up to 10% of cystic fibrosis (CF) children develop cirrhosis by the first decade. We evaluated
the utility of two simple biomarkers, aspartate aminotransferase to platelet ratio index (APRI) …

Normal liver stiffness values in children: a comparison of three different elastography methods

AB Mjelle, A Mulabecirovic, RF Havre… - Journal of pediatric …, 2019 - journals.lww.com
Objectives: Noninvasive tests for the evaluation of liver fibrosis are particularly helpful in
children to avoid general anesthesia and potential complications of invasive tests. We aimed …

Accuracy of transient elastography data combined with APRI in detection and staging of liver disease in pediatric patients with cystic fibrosis

PJ Lewindon, MV Puertolas-Lopez, LE Ramm… - Clinical …, 2019 - Elsevier
Background & Aims Liver disease develops in 15%–72% of patients with cystic fibrosis, and
5%–10% develop cirrhosis or portal hypertension, usually during childhood. Transient …

[HTML][HTML] Acoustic radiation force impulse imaging—normal values of liver stiffness in healthy children

S Hanquinet, D Courvoisier, A Kanavaki, A Dhouib… - Pediatric …, 2013 - Springer
Background Acoustic radiation force impulse imaging (ARFI) is a recent ultrasound
technique to assess tissue stiffness. Objective Our aim was to describe the feasibility and to …