Health consequences of circadian disruption in humans and animal models

JA Evans, AJ Davidson - Progress in molecular biology and translational …, 2013 - Elsevier
Daily rhythms in behavior and physiology are programmed by a hierarchical collection of
biological clocks located throughout the brain and body, known as the circadian system …

[HTML][HTML] Association between long sleep duration and increased risk of obesity and type 2 diabetes: a review of possible mechanisms

X Tan, CD Chapman, J Cedernaes, C Benedict - Sleep medicine reviews, 2018 - Elsevier
For the last two decades research has revealed an alarming association between short
sleep duration and metabolic disorders. In tandem, the hormonal, behavioral, and genetic …

Effects of the internal circadian system and circadian misalignment on glucose tolerance in chronic shift workers

CJ Morris, TE Purvis, J Mistretta… - The Journal of Clinical …, 2016 - academic.oup.com
Context: Shift work is a risk factor for diabetes. The separate effects of the endogenous
circadian system and circadian misalignment (ie, misalignment between the central …

Light at night in older age is associated with obesity, diabetes, and hypertension

M Kim, TH Vu, MB Maas, RI Braun, MS Wolf… - Sleep, 2023 - academic.oup.com
Light at night (LAN) has been associated with negative health consequences and metabolic
risk factors. Little is known about the prevalence of LAN in older adults in the United States …

Dim light at night disrupts molecular circadian rhythms and increases body weight

LK Fonken, TG Aubrecht… - Journal of biological …, 2013 - journals.sagepub.com
With the exception of high latitudes, life has evolved under bright days and dark nights. Most
organisms have developed endogenously driven circadian rhythms that are synchronized to …

Circadian clocks and metabolism

B Marcheva, KM Ramsey, CB Peek, A Affinati, E Maury… - Circadian clocks, 2013 - Springer
Circadian clocks maintain periodicity in internal cycles of behavior, physiology, and
metabolism, enabling organisms to anticipate the 24-h rotation of the Earth. In mammals …

Light at night, clocks and health: from humans to wild organisms

DM Dominoni, JC Borniger, RJ Nelson - Biology letters, 2016 - royalsocietypublishing.org
The increasing use of electric lights has modified the natural light environment dramatically,
posing novel challenges to both humans and wildlife. Indeed, several biomedical studies …

The human circadian system has a dominating role in causing the morning/evening difference in diet‐induced thermogenesis

CJ Morris, JI Garcia, S Myers, JN Yang, N Trienekens… - …, 2015 - Wiley Online Library
Objective Diet‐induced thermogenesis (DIT) is lower in the evening and at night than in the
morning. This may help explain why meal timing affects body weight regulation and why shift …

[HTML][HTML] Circadian regulation of metabolism

SM Bailey, US Udoh, ME Young - Journal of Endocrinology, 2014 - joe.bioscientifica.com
In association with sleep–wake and fasting–feeding cycles, organisms experience dramatic
oscillations in energetic demands and nutrient supply. It is therefore not surprising that …

Hormonally mediated effects of artificial light at night on behavior and fitness: linking endocrine mechanisms with function

JQ Ouyang, S Davies… - Journal of Experimental …, 2018 - journals.biologists.com
Alternation between day and night is a predictable environmental fluctuation that organisms
use to time their activities. Since the invention of artificial lighting, this predictability has been …