Topical drug delivery is a promising approach to treat different skin disorders. However, it
remains a challenge mainly due to the nature and rigidity of the nanosystems, which limit …

Nanocrystals represent an improvement over the traditional nanocarriers for dermal
application, providing the advantages of 100% drug loading, a large surface area, increased …

Two challenges in topical drug delivery to the skin include solubilizing hydrophobic drugs in
water-based formulations and increasing drug penetration into the skin. Polymeric core …

Drug penetration in human skin ex vivo following a modification of skin barrier permeability
is systematically investigated by scanning transmission X-ray microscopy. Element-selective …

Confocal Raman microspectroscopy (CRM) with 633-and 785-nm excitation wavelengths
combined with optical clearing (OC) technique was used for ex-vivo study of porcine skin in …

A combined experimental and theoretical method to simultaneously determine diffusivity and
free-energy profiles of particles that penetrate into inhomogeneous hydrogel systems is …

Nanoparticles are presently considered the efficient carriers of medicals, cosmetics, and
pharmaceuticals in the human organism. There is a lot of research carried out on the …

We introduce an analytical physical description of micro‐spatially offset Raman
spectroscopy (micro‐SORS) experiments in turbid samples with a special emphasis on its …

The effect of glycerol solutions of different concentrations and exposure times on the optical
clearing efficiency in intact pig skin has been studied in the analysis of Raman spectra …

In this research work, we investigate the concentration profiles in the single and the
interconnected multiple-compartment systems with sieve partitions for the transport of …