Natural small molecules in breast cancer treatment: understandings from a therapeutic viewpoint

MR Islam, F Islam, MH Nafady, M Akter, S Mitra, R Das… - Molecules, 2022 - mdpi.com
Breast cancer (BrCa) is the most common malignancy in women and the second most
significant cause of death from cancer. BrCa is one of the most challenging malignancies to …

Metabolic syndrome and risk of cancer: a systematic review and meta-analysis

K Esposito, P Chiodini, A Colao, A Lenzi… - Diabetes …, 2012 - Am Diabetes Assoc
OBJECTIVE Available evidence supports the emerging hypothesis that metabolic syndrome
may be associated with the risk of some common cancers. We did a systematic review and …

Effects of aerobic and resistance exercise on metabolic syndrome, sarcopenic obesity, and circulating biomarkers in overweight or obese survivors of breast cancer: a …

CM Dieli-Conwright, KS Courneya… - Journal of Clinical …, 2018 - ascopubs.org
Purpose Metabolic syndrome is associated with an increased risk of cardiovascular disease,
type 2 diabetes, and breast cancer recurrence in survivors of breast cancer. This …

27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology

ER Nelson, SE Wardell, JS Jasper, S Park… - Science, 2013 - science.org
Hypercholesterolemia is a risk factor for estrogen receptor (ER)–positive breast cancers and
is associated with a decreased response of tumors to endocrine therapies. Here, we show …

Obesity and cancer: local and systemic mechanisms

NM Iyengar, CA Hudis… - Annual review of …, 2015 - annualreviews.org
Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …

Cholesterol and breast cancer pathophysiology

ER Nelson, C Chang, DP McDonnell - Trends in Endocrinology & …, 2014 - cell.com
Cholesterol is a risk factor for breast cancer although the mechanisms by which this occurs
are not well understood. One hypothesis is that dyslipidemia results in increased cholesterol …

Contribution of uric acid to cancer risk, recurrence, and mortality

MA Fini, A Elias, RJ Johnson, RM Wright - Clinical and translational …, 2012 - Springer
Two risk factors for the development and progression of cancers that are amenable to life
style modification are chronic inflammation and the metabolic syndrome. This review …

Metabolic syndrome and postmenopausal breast cancer: systematic review and meta-analysis

K Esposito, P Chiodini, A Capuano, G Bellastella… - Menopause, 2013 - journals.lww.com
Objective The role of metabolic syndrome (MS) and its individual components in
postmenopausal breast cancer (PBC) risk is still unclear. We reviewed and summarized …

Serum lipids and breast cancer risk: a meta-analysis of prospective cohort studies

H Ni, H Liu, R Gao - PloS one, 2015 - journals.plos.org
Purpose Epidemiologic studies exploring causal associations between serum lipids and
breast cancer risk have reported contradictory results. We conducted a meta-analysis of …

Metabolic syndrome and breast cancer prognosis

F Berrino, A Villarini, A Traina, B Bonanni… - Breast cancer research …, 2014 - Springer
Metabolic syndrome (MS), conventionally defined by the presence of at least three out of five
dysmetabolic traits (abdominal obesity, hypertension, low plasma HDL-cholesterol, high …