Sympathetic nervous system overactivity and its role in the development of cardiovascular disease
SC Malpas - Physiological reviews, 2010 - journals.physiology.org
This review examines how the sympathetic nervous system plays a major role in the
regulation of cardiovascular function over multiple time scales. This is achieved through …
regulation of cardiovascular function over multiple time scales. This is achieved through …
Evidence for a critical role of the sympathetic nervous system in hypertension
G Grassi, VS Ram - Journal of the American Society of Hypertension, 2016 - Elsevier
Autonomic cardiovascular control is impaired in hypertension, leading to a reduction in the
parasympathetic tone and to an increase in the sympathetic influences to the heart and …
parasympathetic tone and to an increase in the sympathetic influences to the heart and …
The sympathetic nervous system and blood pressure in humans: implications for hypertension
A neurogenic component to primary hypertension (hypertension) is now well established.
Along with raised vasomotor tone and increased cardiac output, the chronic activation of the …
Along with raised vasomotor tone and increased cardiac output, the chronic activation of the …
Sympathetic nervous activation in obesity and the metabolic syndrome—causes, consequences and therapeutic implications
GW Lambert, NE Straznicky, EA Lambert… - Pharmacology & …, 2010 - Elsevier
The world wide prevalence of obesity and the metabolic syndrome is escalating. Contrary to
earlier experimental evidence, human obesity is characterised by sympathetic nervous …
earlier experimental evidence, human obesity is characterised by sympathetic nervous …
Impact of type 2 diabetes mellitus on sympathetic neural mechanisms in hypertension
RJ Huggett, EM Scott, SG Gilbey, JB Stoker… - Circulation, 2003 - Am Heart Assoc
Background—Essential hypertension (EHT) is a major cardiovascular risk factor, and the
additional presence of type 2 diabetes mellitus (DM2) increases this risk. However, although …
additional presence of type 2 diabetes mellitus (DM2) increases this risk. However, although …
Sympathetic neural activity in hypertension and related diseases
G Grassi - American journal of hypertension, 2010 - academic.oup.com
Background Several hemodynamic variables, such as blood pressure, vascular resistance,
cardiac output, and heart rate, are regulated, among others, by sympathetic cardiovascular …
cardiac output, and heart rate, are regulated, among others, by sympathetic cardiovascular …
Metabolic syndrome: a sympathetic disease?
M Schlaich, N Straznicky, E Lambert… - The lancet Diabetes & …, 2015 - thelancet.com
Metabolic syndrome is associated with adverse health outcomes and is a growing problem
worldwide. Although efforts to harmonise the definition of metabolic syndrome have helped …
worldwide. Although efforts to harmonise the definition of metabolic syndrome have helped …
Sympathetic neural activation in nondiabetic metabolic syndrome and its further augmentation by hypertension
RJ Huggett, J Burns, AF Mackintosh, DASG Mary - Hypertension, 2004 - Am Heart Assoc
Hypertension is a major cardiovascular risk factor in the metabolic syndrome (MS) in which
the presence of insulin resistance, glucose intolerance, abnormal lipoprotein metabolism …
the presence of insulin resistance, glucose intolerance, abnormal lipoprotein metabolism …
Neuroinflammation and sympathetic overactivity: Mechanisms and implications in hypertension
Essential hypertension is a multifactorial disorder with a strong genetic predisposition.
Although anti-hypertensive medications have drastically reduced cardiovascular diseases …
Although anti-hypertensive medications have drastically reduced cardiovascular diseases …
Aortic pulse wave velocity as a marker of cardiovascular disease in subjects over 70 years old
S Meaume, A Rudnichi, A Lynch, C Bussy… - Journal of …, 2001 - journals.lww.com
Background Aortic pulse wave velocity (PWV) is a significant and independent predictor of
cardiovascular diseases (CVD) in hypertensive subjects and in patients with end-stage renal …
cardiovascular diseases (CVD) in hypertensive subjects and in patients with end-stage renal …