Multifunctional hydrogels based on chitosan, hyaluronic acid and other biological macromolecules for the treatment of inflammatory bowel disease: A review

Y Ouyang, J Zhao, S Wang - International journal of biological …, 2023 - Elsevier
Hydrogel is a three-dimensional network polymer material rich in water. It is widely used in
the biomedical field because of its unique physical and chemical properties and good …

IBD disease-modifying therapies: insights from emerging therapeutics

NG Kotla, Y Rochev - Trends in Molecular Medicine, 2023 - cell.com
Inflammatory bowel disease (IBD) pathogenesis is associated with gut mucosal
inflammation, epithelial damage, and dysbiosis leading to a dysregulated gut mucosal …

Glycosaminoglycan-based hydrogel delivery system regulates the wound microenvironment to rescue chronic wound healing

X Zhang, J Feng, W Feng, B Xu, K Zhang… - … Applied Materials & …, 2022 - ACS Publications
Chronic wounds cannot proceed through the normal, orderly, and timely sequence of repair.
The adverse cycle between excess reactive oxide species (ROS) and a persistent …

Natural polymer‐derived bioscaffolds for peripheral nerve regeneration

H Zhang, J Guo, Y Wang, L Shang… - Advanced Functional …, 2022 - Wiley Online Library
In recent decades, artificial nerve scaffolds have become a promising substitute for
peripheral nerve repair. Considerable efforts have been devoted to improving the …

Polysaccharide-based nanocarriers for efficient transvascular drug delivery

M Zhang, H Ma, X Wang, B Yu, H Cong… - Journal of Controlled …, 2023 - Elsevier
Polysaccharide-based nanocarriers (PBNs) are the focus of extensive investigation because
of their biocompatibility, low cost, wide availability, and chemical versatility, which allow a …

Hyaluronic acid‐based Bioconjugate systems, Scaffolds, and their therapeutic potential

NG Kotla, IL Mohd Isa, A Larrañaga… - Advanced …, 2023 - Wiley Online Library
In recent years, the development of hyaluronic acid or hyaluronan (HA) based scaffolds,
medical devices, bioconjugate systems have expanded into a broad range of research and …

Hyaluronic acid in the treatment of dry eye disease

L Hynnekleiv, M Magno… - Acta …, 2022 - Wiley Online Library
Dry eye disease (DED) is a highly prevalent and debilitating condition affecting several
hundred million people worldwide. Hyaluronic acid (HA) is a naturally occurring …

A solid–liquid composite lubricating “nano‐snowboard” for long‐acting treatment of osteoarthritis

W Qiu, W Zhao, L Zhang, H Wang, N Li… - Advanced Functional …, 2022 - Wiley Online Library
Osteoarthritis is a chronic inflammatory disease characterized by cartilage degeneration.
Anti‐inflammatory therapy has limited effects, and effective reduction of cartilage wear …

Application of biomolecules modification strategies on PEEK and its composites for osteogenesis and antibacterial properties

X Han, W Gao, Z Zhou, S Yang, J Wang, R Shi… - Colloids and Surfaces B …, 2022 - Elsevier
As orthopedic and dental implants, polyetheretherketone (PEEK) is expected to be a
common substitute material of titanium (Ti) and its alloys due to its good biocompatibility …

Modulation of gut barrier functions in ulcerative colitis by hyaluronic acid system

NG Kotla, ILM Isa, S Rasala, S Demir… - Advanced …, 2022 - Wiley Online Library
The active stages of intestinal inflammation and the pathogenesis of ulcerative colitis are
associated with superficial mucosal damage and intermittent wounding that leads to …