Sepsis has evolved as an enormous health issue amongst critically ill patients. It is a major
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …

Acute kidney injury (AKI) is an important health problem, affecting 13.3 million
individuals/year. It is associated with increased mortality, mainly in low-and middle-income …

Our earlier studies indicated that reactive oxygen species (ROS) were involved in
lipopolysaccharide (LPS)-induced acute kidney injury (AKI). The present study aimed to …

Sepsis is a systemic inflammatory state in response to infection, and concomitant acute
kidney injury (AKI) significantly increases morbidity and mortality. Growing evidence …

Cytosolic proteins are required for regulation of NADPH (nicotinamide adenine dinucleotide
phosphate) oxidase (Nox) isozymes. Here we show that Src homology 3 (SH3) domain …

High-density lipoproteins (HDLs) are a class of blood particles, principally involved in
mediating reverse cholesterol transport from peripheral tissue to liver. Omics approaches …

Acute kidney injury (AKI) is a common complication following severe sepsis, its incidence is
increasing, and it is associated with a high rate of morbidity and mortality. Rutin is a …

Lipopolysaccharide, the main component of the outer membrane of Gram-negative bacteria
is a highly potent endotoxin responsible for organ dysfunction in sepsis. It is present in the …

Acute kidney injury (AKI) is a progressive renal complication which significantly affects the
patient's life with huge economic burden. Untreated acute kidney injury eventually …

Sepsis is a severe inflammatory condition that can cause organ dysfunction, including acute
kidney injury (AKI). Hesperetin is a flavonoid aglycone that has potent antioxidant and anti …