The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Advances in RNA-sequencing techniques have led to the discovery of thousands of non-
coding transcripts with unknown function. There are several types of non-coding linear …

Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

Recent research has demonstrated that the non-coding genome plays a key role in genetic
programming and gene regulation during development as well as in health and …

The discovery of thousands of noncoding RNAs (ncRNAs) has expanded our view on
mammalian genomes and transcriptomes, as well as their organization and regulation …

Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …

PIWI-interacting RNAs (piRNAs) are abundantly expressed during cardiac hypertrophy.
However, their functions and molecular mechanisms remain unknown. Here, we identified a …

RNA modulation has become a promising therapeutic approach for the treatment of several
types of disease. The emerging field of noncoding RNA-based therapies has now come to …

RNA has emerged as the prime target for diagnostics, therapeutics and the development of
personalized medicine. In particular, the non-coding RNAs (ncRNAs) that do not encode …

The nuclear paraspeckle assembly transcript 1 (NEAT1, a long non-coding RNA) is
frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with …