Applications for α-lactalbumin in human nutrition

DK Layman, B Lönnerdal, JD Fernstrom - Nutrition reviews, 2018 - academic.oup.com
Abstract α-Lactalbumin is a whey protein that constitutes approximately 22% of the proteins
in human milk and approximately 3.5% of those in bovine milk. Within the mammary gland, α …

Fatty acids as antibiofilm and antivirulence agents

P Kumar, JH Lee, H Beyenal, J Lee - Trends in microbiology, 2020 - cell.com
Fatty acids (FAs) have emerged as a potential alternative to conventional antibiotics. Since
many microbes respond differently to a variety of natural and synthetic FAs, substantial …

Oleic acid induces apoptosis and autophagy in the treatment of Tongue Squamous cell carcinomas

L Jiang, W Wang, Q He, Y Wu, Z Lu, J Sun, Z Liu… - Scientific reports, 2017 - nature.com
Oleic acid (OA), a main ingredient of Brucea javanica oil (BJO), is widely known to have
anticancer effects in many tumors. In this study, we investigated the anticancer effect of OA …

Anti-tumor Effect of Oleic Acid in Hepatocellular Carcinoma Cell Lines via Autophagy Reduction

F Giulitti, S Petrungaro, S Mandatori… - Frontiers in Cell and …, 2021 - frontiersin.org
Oleic acid (OA) is a component of the olive oil. Beneficial health effects of olive oil are well-
known, such as protection against liver steatosis and against some cancer types. In the …

α-Lactalbumin, amazing calcium-binding protein

EA Permyakov - Biomolecules, 2020 - mdpi.com
α-Lactalbumin (α-LA) is a small (Mr 14,200), acidic (pI 4–5), Ca2+-binding protein. α-LA is a
regulatory component of lactose synthase enzyme system functioning in the lactating …

Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

TJ Sargeant, B Lloyd-Lewis, HK Resemann… - Nature cell …, 2014 - nature.com
We have previously demonstrated that Stat3 regulates lysosomal-mediated programmed
cell death (LM-PCD) during mouse mammary gland involution in vivo. However, the …

[HTML][HTML] Membrane composition and dynamics: a target of bioactive virgin olive oil constituents

S Lopez, B Bermudez, S Montserrat-De La Paz… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The endogenous synthesis of lipids, which requires suitable dietary raw materials, is critical
for the formation of membrane bilayers. In eukaryotic cells, phospholipids are the …

Bovine β-lactoglobulin/fatty acid complexes: binding, structural, and biological properties

S Le Maux, S Bouhallab, L Giblin, A Brodkorb… - Dairy science & …, 2014 - Springer
Ligand-binding properties of β-lactoglobulin (β-lg) are well documented, but the subsequent
biological functions are still unclear. Focusing on fatty acids/β-lg complexes, the structure …

Bioactive properties of milk proteins in humans: A review

AB Nongonierma, RJ FitzGerald - Peptides, 2015 - Elsevier
Many studies have demonstrated that milk protein consumption has benefits in terms of
promoting human health. This review assesses the intervention studies which have …

[HTML][HTML] Anticancer and antimicrobial effects of novel ciprofloxacin fatty acids conjugates

A Chrzanowska, P Roszkowski, A Bielenica… - European journal of …, 2020 - Elsevier
Ciprofloxacin (CP) has a confirmed cytotoxic action on some cancerous cells, but in high,
non-pharmacological concentrations. Considering features of natural fatty acids, such as …