Paracetamol use during pregnancy—a call for precautionary action

AZ Bauer, SH Swan, D Kriebel, Z Liew… - Nature Reviews …, 2021 - nature.com
Abstract Paracetamol (N-acetyl-p-aminophenol (APAP), otherwise known as
acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to …

The congenital and acquired mechanisms implicated in the etiology of central precocious puberty

VN Brito, APM Canton, CE Seraphim… - Endocrine …, 2023 - academic.oup.com
The etiology of central precocious puberty (CPP) is multiple and heterogeneous, including
congenital and acquired causes that can be associated with structural or functional brain …

[HTML][HTML] Endocrine disruptors and the male reproductive system

JB Stukenborg, RT Mitchell, O Söder - Best Practice & Research Clinical …, 2021 - Elsevier
In recent years, there has been an increased incidence in several of the most common
reproductive disorders, including hypospadias and cryptorchidism in newborns, and …

The main changes in pregnancy—therapeutic approach to musculoskeletal pain

F Fiat, PE Merghes, AD Scurtu, B Almajan Guta… - Medicina, 2022 - mdpi.com
Background and Objectives: During pregnancy, women undergo various physiological and
anatomical changes that are accentuated as the pregnancy progresses, but return to their …

Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety

A Zafeiri, RT Mitchell, DC Hay… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Analgesia during pregnancy is often necessary. Due to their widespread
availability, many mothers opt to use over-the-counter (OTC) analgesics. Those analgesic …

Long-term safety of prenatal and neonatal exposure to paracetamol: a systematic review

R Patel, K Sushko, J van den Anker… - International Journal of …, 2022 - mdpi.com
Introduction: Paracetamol is the most commonly used antipyretic and analgesic in
pregnancy. It is also increasingly used off-label in the neonatal intensive care unit. Despite …

[HTML][HTML] Using experimental models to decipher the effects of acetaminophen and NSAIDs on reproductive development and health

B Boizet-Bonhoure, S Déjardin, M Rossitto… - Frontiers in …, 2022 - frontiersin.org
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin (acetylsalicylic acid),
diclofenac and ibuprofen (IBU), and analgesic drugs, such as acetaminophen (APAP, or …

Intrauterine exposure to acetaminophen and adverse developmental outcomes: epidemiological findings and methodological issues

Z Liew, A Ernst - Current Environmental Health Reports, 2021 - Springer
Abstract Purpose of Review Acetaminophen (or paracetamol) is one of the most commonly
used medications during pregnancy. We reviewed recent epidemiological evidence …

Potential adverse actions of prenatal exposure of acetaminophen to offspring

K Wu, W Lu, X Yan - Frontiers in Pharmacology, 2023 - frontiersin.org
Acetaminophen (APAP) is a widely used as analgesic and antipyretic drug. APAP is also
added as an active ingredient in various medications to relieve pain and reduce fever. APAP …

Cohort profile: the puberty cohort in the Danish National Birth Cohort (DNBC)

A Ernst, N Brix, LLB Lauridsen… - International Journal …, 2020 - academic.oup.com
In 2012, the DNBC Puberty Cohort was established as a longitudinal sub-cohort within the
DNBC. Children eligible for sampling were singletons born into the DNBC between 2000 …