The prevalence of Alzheimer's disease (AD) continues to rise due to the increasing aging
population. Among the various genetic factors associated with AD, apolipoprotein E (ApoE) …

Gut microbiota is the largest and most complex microflora in the human body, which plays a
crucial role in human health and disease. Over the past 20 years, the bidirectional …

Background According to some recent observational studies, the gut microbiota influences
atherosclerosis via the gut microbiota-artery axis. However, the causal role of the gut …

Atherosclerosis, a highly prevalent cardiovascular disease, has significantly contributed to
morbidity and mortality worldwide. Despite the availability of various treatment options in …

Dysregulation of lipid metabolism results in metabolism-related diseases. Our previous
research indicated that 1.3% E and 4% E ruminant trans fatty acids (R-TFA) caused …

The current body of research points to a notable correlation between an imbalance in gut
microbiota and the development of type 2 diabetes mellitus (T2D) as well as its …

Electrical stimulation (ES) is a safe and effective procedure in clinical rehabilitation with few
adverse effects. However, studies on ES for atherosclerosis (AS) are scarce because ES …

Phytosterol (PS) is a steroid, and its bioavailability can be enhanced by interacting with
protein in the C-24 hydroxyl group. The interaction between sterols and amino acid residues …

Doxorubicin (DOX) is a broad-spectrum and highly efficient anticancer agent, but its clinical
implication is limited by lethal cardiotoxicity. Growing evidences have shown that alterations …

In vitro digestion models, as innovative assessment tools, possess advantages such as
speed, high throughput, low cost, and high repeatability. They have been widely applied to …