[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

The epigenetics of migraine

F Zobdeh, II Eremenko, MA Akan, VV Tarasov… - International Journal of …, 2023 - mdpi.com
Migraine is a complex neurological disorder and a major cause of disability. A wide range of
different drug classes such as triptans, antidepressants, anticonvulsants, analgesics, and …

Gestational folic acid supplement prevents vitamin D deficiency-induced depression-like behavior by reversing cortical DNA hypomethylation in adult offspring

LJ Tuo, XY Song, YY Zhu, HN He, YP Song… - The Journal of Steroid …, 2023 - Elsevier
Depression is a common mental disorder with an increasing incidence. Several studies
have demonstrated that cortical DNA hypomethylation is associated with depression-like …

Mental health and the effects on methylation of stress-related genes in front-line versus other health care professionals during the second wave of COVID-19 …

S Tabano, L Tassi, MG Cannone, G Brescia… - European Archives of …, 2023 - Springer
Healthcare workers experienced high degree of stress during COVID-19. Purpose of the
present article is to compare mental health (depressive and Post-Traumatic-Stress …

The role of genetics in the development and pharmacotherapy of depression and its impact on drug discovery

A Zięba, D Matosiuk, AA Kaczor - International journal of molecular …, 2023 - mdpi.com
Complex disorders, such as depression, remain a mystery for scientists. Although genetic
factors are considered important for the prediction of one's vulnerability, it is hard to estimate …

[HTML][HTML] The role of Gadd45b in neurologic and neuropsychiatric disorders: An overview

X Shen, S Shi, H Li, C Wang, Y Zhang, H Yu… - Frontiers in Molecular …, 2022 - frontiersin.org
Growth arrest and DNA damage-inducible beta (Gadd45b) is directly intertwined with stress-
induced DNA repair, cell cycle arrest, survival, and apoptosis. Previous research on …

Artificial neural networks reveal sex differences in gene methylation, and connections between maternal risk factors and symptom severity in autism spectrum disorder

A Stoccoro, R Gallo, S Calderoni, R Cagiano… - …, 2022 - Future Medicine
Aim and methods: Artificial neural networks were used to unravel connections among blood
gene methylation levels, sex, maternal risk factors and symptom severity evaluated using the …

[HTML][HTML] Correlation of the methylomic signature of smoking during pregnancy with clinical traits in ADHD

B Chaumette, N Grizenko, W Fageera, MÈ Fortier… - Journal of Psychiatry and …, 2023 - jpn.ca
Background: Attention deficit/hyperactivity disorder (ADHD) is a highly prevalent childhood
disorder. Maternal smoking during pregnancy is a replicated environmental risk factor for …

[HTML][HTML] A pilot investigation of differential hydroxymethylation levels in patient-derived neural stem cells implicates altered cortical development in bipolar disorder

A Kumar, MZ Kos, D Roybal, MA Carless - Frontiers in psychiatry, 2023 - frontiersin.org
Introduction Bipolar disorder (BD) is a chronic mental illness characterized by recurrent
episodes of mania and depression and associated with social and cognitive disturbances …

DNA Methylation Patterns in Relation to Acute Severity and Duration of Anxiety and Depression

E Vidovič, S Pelikan, M Atanasova, K Kouter… - Current Issues in …, 2023 - mdpi.com
Depression and anxiety are common mental disorders that often occur together. Stress is an
important risk factor for both disorders, affecting pathophysiological processes through …