The global problem of antifungal resistance: prevalence, mechanisms, and management

DS Perlin, R Rautemaa-Richardson… - The Lancet infectious …, 2017 - thelancet.com
All serious fungal infections need appropriate antifungal therapy for successful patient
outcome. Only a few classes of antifungal drugs are available, so the emergence of …

Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Epidemiology and Outcomes of Invasive Candidiasis Due to Non-albicans Species of Candida in 2,496 Patients: Data from the Prospective Antifungal Therapy …

MA Pfaller, DR Andes, DJ Diekema, DL Horn… - PloS one, 2014 - journals.plos.org
This analysis describes the epidemiology and outcomes of invasive candidiasis caused by
non-albicans species of Candida in patients enrolled in the Prospective Antifungal Therapy …

Forgotten fungi—the gut mycobiome in human health and disease

CE Huseyin, PW O'Toole, PD Cotter… - FEMS Microbiology …, 2017 - academic.oup.com
The human body is home to a complex and diverse microbial ecosystem that plays a central
role in host health. This includes a diversity of fungal species that is collectively referred to …

ESCMID and ECMM joint guidelines on diagnosis and management of hyalohyphomycosis: Fusarium spp., Scedosporium spp. and others

AM Tortorano, M Richardson, E Roilides… - Clinical Microbiology …, 2014 - Wiley Online Library
Mycoses summarized in the hyalohyphomycosis group are heterogeneous, defined by the
presence of hyaline (non‐dematiaceous) hyphae. The number of organisms implicated in …

ESCMID and ECMM joint clinical guidelines for the diagnosis and management of rare invasive yeast infections

MC Arendrup, T Boekhout, M Akova… - Clinical Microbiology …, 2014 - Wiley Online Library
The mortality associated with invasive fungal infections remains high with that involving rare
yeast pathogens other than C andida being no exception. This is in part due to the severe …

Emerging opportunistic yeast infections

MH Miceli, JA Díaz, SA Lee - The Lancet infectious diseases, 2011 - thelancet.com
A growing population of immunosuppressed patients has resulted in increasingly frequent
diagnoses of invasive fungal infections, including those caused by unusual yeasts. The …

Epidemiology of invasive candidiasis: a persistent public health problem

MA Pfaller, DJ Diekema - Clinical microbiology reviews, 2007 - Am Soc Microbiol
Invasive candidiasis (IC) is a leading cause of mycosis-associated mortality in the United
States. We examined data from the National Center for Health Statistics and reviewed recent …

Epidemiology of invasive mycoses in North America

MA Pfaller, DJ Diekema - Critical reviews in microbiology, 2010 - Taylor & Francis
The incidence of invasive mycoses is increasing, especially among patients who are
immunocompromised or hospitalized with serious underlying diseases. Such infections may …

Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-Year Analysis of Susceptibilities of Candida Species to Fluconazole and …

MA Pfaller, DJ Diekema, DL Gibbs… - Journal of clinical …, 2010 - Am Soc Microbiol
Fluconazole in vitro susceptibility test results for 256,882 isolates of Candida spp. were
collected from 142 sites in 41 countries from June 1997 to December 2007. Data were …