Mannose binding lectin (MBL) is a collagenous C-type lectin, which plays an important role
in innate immunity. It can bind to carbohydrates on the surface of a wide range of pathogens …

Virulent strains of Escherichia coli (Avian Pathogenic E. Coli: APEC) can cause initial
infection of the respiratory tract in chickens potentially leading to systemic infection called …

The air-liquid interface of the mammalian lung is lined with pulmonary surfactants, a mixture
of specific proteins and lipids that serve a dual purpose-enabling air-breathing and …

The respiratory tract is continuously challenged by aerosols which contain particulate
material and nonpathogenic microorganisms and may also carry pathogens of significant …

As the target organ for numerous pathogens, the lung epithelium exerts critical functions in
health and disease. However, research in this area has been hampered by the quiescence …

Chicken surfactant protein A (cSP-A) is a collectin believed to play an important role in
antiviral immunity. However, cSP-A expression in the respiratory tract of chickens after viral …

The pulmonary system develops from a series of complex events that involve coordinated
growth and differentiation of distinct cellular compartments. After lung specification of the …

The host innate defense–pathogen interaction in the lung has always been a topic of
concern. The respiratory tract is a common entry route for Avian pathogenic Escherichia coli …

Pulmonary collectins have been reported to bind carbohydrates on pathogens and inhibit
infection by agglutination, neutralization, and opsonization. In this study, surfactant protein A …

Chicken surfactant protein A (cSP-A) and chicken lung lectin (cLL) are C-type lectins that
play important roles in pulmonary host defense responses. Herein, we explored the …