[HTML][HTML] The role and mechanism of essential selenoproteins for homeostasis

R Ye, J Huang, Z Wang, Y Chen, Y Dong - Antioxidants, 2022 - mdpi.com
Selenium (Se) is one of the essential trace elements that plays a biological role in the body,
mainly in the form of selenoproteins. Selenoproteins can be involved in the regulation of …

[HTML][HTML] Hepatocellular carcinoma and obesity, type 2 diabetes mellitus, cardiovascular disease: Causing factors, molecular links, and treatment options

C Zhang, S Liu, M Yang - Frontiers in Endocrinology, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, which will
affect more than a million people by the year 2025. However, current treatment options have …

Selenium nanoparticles overcomes sorafenib resistance in thioacetamide induced hepatocellular carcinoma in rats by modulation of mTOR, NF-κB pathways and …

TM Al-Noshokaty, NM Mesbah, DM Abo-Elmatty… - Life Sciences, 2022 - Elsevier
Aims The first-line treatment for advanced hepatocellular carcinoma (HCC) is the
multikinase inhibitor sorafenib (SOR). Sofafenib resistance is linked to protein kinase …

Morphology-directed radiosensitization of MoSe2 nanoplatforms for promoting cervical cancer radiotherapy

W Jiang, Z Zhang, M Ye, S Pan, G Huang, T Chen… - Nano Today, 2022 - Elsevier
Radioresistance has been the main obstacle of cervical cancer radiotherapy. Hence, it's
urgent need to develop effective radiosensitizers for improving the radiotherapeutic efficacy …

[HTML][HTML] “Alphabet” Selenoproteins: Implications in Pathology

CB Dogaru, C Duță, C Muscurel, I Stoian - International Journal of …, 2023 - mdpi.com
Selenoproteins are a group of proteins containing selenium in the form of selenocysteine
(Sec, U) as the 21st amino acid coded in the genetic code. Their synthesis depends on …

Homology of selenium (Se) and tellurium (Te) endow the functional similarity of Se-doped and Te-doped mesoporous bioactive glass nanoparticles in bone tissue …

Y Zhang, M Hu, W Zhang, X Zhang - Ceramics International, 2022 - Elsevier
The focus of bone tissue engineering is to realize the regeneration of new functional bone
through the synergistic combination of biomaterials, therapeutic agents and cells. Doping of …

SNPs in 3′ UTR miRNA Target Sequences Associated with Individual Drug Susceptibility

E Rykova, N Ershov, I Damarov… - International Journal of …, 2022 - mdpi.com
The complementary interaction of microRNAs (miRNAs) with their binding sites in the 3′
untranslated regions (3′ UTRs) of target gene mRNAs represses translation, playing a …

[HTML][HTML] Distribution characteristics of organic selenium in Se-enriched Lactobacillus (Lactobacillus paracasei)

Y Sun, H Wang, L Zhou, M Chang, T Yue, Y Yuan… - LWT, 2022 - Elsevier
The accumulation of organic selenium (Se) by lactic acid bacteria (LAB) showed excellent
biosafety and absorption efficiency. Identification of Se-enriched strains and the production …

Iron Single-Atom nanocatalysts in response to tumor microenvironment for highly efficient Chemo-chemodynamic therapy

T Li, L Chen, X Fu, Z Liu, S Zhu, Y Chen… - Journal of Industrial and …, 2022 - Elsevier
Chemodynamic therapy (CDT) based on multifunctional nanoparticles (NPs) has occurred
as an attractive cancer treatment that covers the shortage of nonnegligible limitations from …

[HTML][HTML] Characterization, selenylation, and antineoplastic effects on HepG2 cells in vitro and in vivo of an arabinofuranan from the fruits of Akebia quinata

H Wang, Z Lin, Y Li, X Wang, J Xu, Y Guo - Arabian Journal of Chemistry, 2023 - Elsevier
Akebia quinata is a traditional medicinal plant distributed in East Asia and its fruits are
applicated in food and pharmaceutical fields. Herein, a novel polysaccharide (AQP70-2A) …