[HTML][HTML] Advances and opportunities in malaria population genomics

DE Neafsey, AR Taylor, BL MacInnis - Nature Reviews Genetics, 2021 - nature.com
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

[HTML][HTML] Antimalarial drug resistance and implications for the WHO global technical strategy

MM Ippolito, KA Moser, JBB Kabuya… - Current epidemiology …, 2021 - Springer
Abstract Purpose of Review Five years have passed since the World Health Organization
released its Global Technical Strategy for Malaria (GTS). In that time, progress against …

[HTML][HTML] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

A Ahouidi, M Ali, J Almagro-Garcia… - Wellcome Open …, 2021 - ncbi.nlm.nih.gov
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

[HTML][HTML] Measurably recombining malaria parasites

F Camponovo, CO Buckee, AR Taylor - Trends in parasitology, 2023 - cell.com
Genomic epidemiology has guided research and policy for various viral pathogens and
there has been a parallel effort towards using genomic epidemiology to combat diseases …

[HTML][HTML] Malaria surveillance reveals parasite relatedness, signatures of selection, and correlates of transmission across Senegal

SF Schaffner, A Badiane, A Khorgade, M Ndiop… - Nature …, 2023 - nature.com
We here analyze data from the first year of an ongoing nationwide program of genetic
surveillance of Plasmodium falciparum parasites in Senegal. The analysis is based on 1097 …

Sensitive, Highly Multiplexed Sequencing of Microhaplotypes From the Plasmodium falciparum Heterozygome

SK Tessema, NJ Hathaway, NB Teyssier… - The Journal of …, 2022 - academic.oup.com
Background Targeted next-generation sequencing offers the potential for consistent, deep
coverage of information-rich genomic regions to characterize polyclonal Plasmodium …

[HTML][HTML] Implementing parasite genotyping into national surveillance frameworks: feedback from control programmes and researchers in the Asia–Pacific region

R Noviyanti, O Miotto, A Barry, J Marfurt, S Siegel… - 2020 - Springer
Abstract The Asia–Pacific region faces formidable challenges in achieving malaria
elimination by the proposed target in 2030. Molecular surveillance of Plasmodium parasites …

[HTML][HTML] Drug resistance of Plasmodium falciparum and Plasmodium vivax isolates in Indonesia

FV Rahmasari, PBS Asih, FK Dewayanti… - Malaria Journal, 2022 - Springer
This review article aims to investigate the genotypic profiles of Plasmodium falciparum and
Plasmodium vivax isolates collected across a wide geographic region and their association …

Malaria molecular surveillance in the Peruvian Amazon with a novel highly multiplexed Plasmodium falciparum AmpliSeq assay

JH Kattenberg, C Fernandez-Miñope… - Microbiology …, 2023 - Am Soc Microbiol
Molecular surveillance for malaria has great potential to support national malaria control
programs (NMCPs). To bridge the gap between research and implementation, several …

Describing the current status of Plasmodium falciparum population structure and drug resistance within mainland Tanzania using molecular inversion probes

KA Moser, RA Madebe, O Aydemir… - Molecular …, 2021 - Wiley Online Library
High‐throughput Plasmodium genomic data is increasingly useful in assessing prevalence
of clinically important mutations and malaria transmission patterns. Understanding parasite …