Isolamento, caracterização bioquímica e avaliação do potencial inflamatório de uma proteína secretada rica em cisteína (CRISP) da peçonha de Bothrops jararaca

ME Lodovicho - 2015 - teses.usp.br
Envenenamentos por serpentes do gênero Bothrops provocam reações sistêmicas e locais
como coagulopatias, hemorragias, reação inflamatória, dor e mionecrose. Proteínas …

Análise do transcriptoma das glândulas venenosas do escorpião Tityus stigmurus

DD Almeida - 2011 - repositorio.ufrn.br
No Brasil, acidentes com escorpiões são considerados de importância médicosanitária, não
somente por sua incidência, mas também pela potencialidade do veneno de algumas …

Aplicação de nanopartículas de quitosana com potencial de adjuvante na produção de soro contra o venneno do escorpião Tityus serrulatus

KSR Soares - 2012 - repositorio.ufrn.br
No Brasil, diversas espécies de escorpiões são conhecidas por provocar acidentes que
podem levar ao óbito, sendo estas pertencentes principalmente ao gênero Tityus. O …

Maurotoxin, PI1 and HSTX1 derivatives

JM Sabatier, K Mabrouk, H Rochat - US Patent 7,829,666, 2010 - Google Patents
Derivatives of Maurotoxin (MTX) in which the native disulfide bridge pattern (Cys3-Cys24,
Cys9-Cys29, Cys19, Cys31-Cys34) has been disrupted are useful for the treatment of …

[PDF][PDF] unesp

EPED DO PERFIL, DE DE METABÓLITOS… - 2016 - repositorio.unesp.br
Numerous studies produced in the last 30 years, come elucidating structures and biological
activities of various components of animal venoms, showing their complex compositions …

LA SYNTHESE PEPTIDIQUE EN PHASE SOLIDE: INTERET DANS LA VALORISATION DES SUBSTANCES MOLECULAIRES ISSUES DE VENINS ANIMAUX

S Aidi-Knani, H Ghodhbane, C Mourre… - Archives de l'Institut …, 2014 - search.proquest.com
Toxins from animal venoms are small peptide molecules able to interact with a wide range of
specific cellular targets in order to modulate their activity, which enables them to act in many …

Strategies toward structural and functional 'optimization'of animal peptide toxins

N Andreotti, H Ziadi, S Mouhat, M De Waard… - International Journal of …, 2012 - ajol.info
Background: venoms of a variety of animal species (ie scorpions, snakes, spiders, sea
anemones, marine cone snails, worms, and insects) are rich sources of bioactive …

[PDF][PDF] Design of a disulfide-less, pharmacologically inert, and chemically competent analog of maurocalcine for the efficient transport of impermeant compounds into …

R Narendra, W Norbert, TN Isabelle, A Sonia, A Nicolas… - Citeseer
Maurocalcine is a 33-mer peptide initially isolated from the venom of a Tunisian scorpion. It
has proved itself valuable as a pharmacological activator of the ryanodine receptor, and has …

[PDF][PDF] Evaluation of SNAREs and K+ channels as targets for novel therapeutics

S Ní Dhochartaigh - 2009 - doras.dcu.ie
Rheumatoid arthritis (RA) is the most common auto-immune disease (Nishimoto and
Kishimoto, 2004), affecting 1% of the population (McInnes and Schett, 2007). Despite this …

[引用][C] Effect of Cu 2 on the Oxidative Folding of Synthetic Maurotoxin in Vitro

JM SABATIER, E DI LUCCIO, M DE WAARD